Organic Analysis: Mass Spectrometry

Question 1

What can mass spectrometry measure?

Answer 1

• It can determine the molecular formula of a compound

- It gives the m/z value of a compound, which is equal to its Mr

Question 2

What is high resolution mass spectrometry?

Answer 2

• Can measure m/z and Mr to several decimal places
• Can distinguish compounds with same Mr but different empirical formula
• E.g propane (C3H8) and ethanal (CH3CHO)

Question 3

How do you calculate atomic masses using high resolution mass spectrometry?

Answer 3

• Same as calculating Mr

- Atomic masses are just given to higher degree of accuracy