Oral squamous cell carcinoma - Pathology Flashcards
1
Q
What percentage of oral cancers does this make up?
A
> 90%
2
Q
What are the variable presentations of oral squamous cell carcinoma?
A
White Red Speckled Ulcer Lump
3
Q
What are the high risk sites in the mouth for oral squamous cell carcinoma?
A
Floor of the mouth Lateral border and ventral tongue Soft palate Retromolar pad Tonsular pillars
4
Q
Aetiological factors for SSC?
A
Tobacco Alcohol HPV 16 and 18 Chronic infections Nutritional deficiencies Genetics Post transplant A patient with a history of a primary oral SSC is at increased risk of developing a new second primary SSC
5
Q
How are SSCs graded?
A
By degree of differentiation:
Well differentiated: very obviously squamous cells
moderately differentiated
poorly differentiated: may be difficult to identify tumour cells as epithelial
6
Q
What is the treatment for SSC?
A
Surgery with or without adjuvant therapy
7
Q
What is the five year survival of SSC?
A
40-50%
