Oral Pathology/biopsy studies Flashcards

1
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

Which 3 of their 8 categories comprised the vast majority of lesions?

A

reactive lesions

benign neoplasms

malignant neoplasms

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2
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What were proportions of reactive lesions, benign neoplasms and malignant neoplasms?

A

Reactive 39%

Benign 27%

Malignant 15%

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3
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What was the most common reactive lesion?

A

Gingival fibrous hyperplasia (24% of biopsies)

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4
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What were the two most common benign tumors?

A

POF 21%

CAA 4%

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5
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What were the proportions of malignant tumors?

A

MM - 8%

Various sarcomas - 5%

SCC - 1.4%

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6
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What was the authors theory for why their numbers of SCC were much lower than other reports?

A

Thy are specifically an oral pathology lab and work primarily with dentists. SCC may be being seen by other specialists and sent to other labs.

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7
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What breed predispositions were noted?

A

Boxer - POF

Dachshund - malignant tumors

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8
Q

According to L. Svendenius, DVM; G.Warfvinge, DDS, PhD in

Oral Pathology in Swedish Dogs: A Retrospective Study of 280 Biopsies,

What sex predelictions were noted?

A

slight inclination for males to have malignant tumors and for females to have POF

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9
Q

Kipp Wingo JVD 2018 #1

Rank the following lesions in cats from most to least common:

Malignant tumors; inflammatory lesions; odontogenic tumors

A
  • 51% inflammatory
  • 47% malignant neoplasm (of which 27/37 are SCC - 37% of total)
  • 3% odontogenic
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10
Q

Kipp Wingo JVD 2018 #1

Rank the following lesions in dogs from most to least common:

Odontogenic Tumors, malignant neoplasm, inflammatory lesions

A
  • 37% malignant neoplasia
  • 34% odontogenic tumors,
  • 28% inflammatory,
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11
Q

Kipp Wingo JVD 2018 #1

Of the odontogenic lesions diagnosed in dogs, rank the following from most to least frequent:

Odontogenic cyst; CAA; POF;

A
  • POF 18% of biopsies
  • CAA 14% of biopsies
  • Odontigenic cyst 2% of biopsies
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12
Q

Kipp Wingo JVD 2018 #1

What differences were detected between this study and the UC davis data (reported biopsies for 1995-2001) with regards to the prevalence of odontogenic tumors in biopsy samples, and what is the likely origin of the discrepancy?

A

This study had more odontogenic tumors (34% versus 13%) In the UC Davis data they had a category for hyperplasias, which included POF’s separate from odontogenic tumors.

Note that this is the table from verstraete chapter 39, NOT the Fiani article Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995–2005) (which is also important)

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13
Q

Kipp Wingo JVD 2018 #1

In this study rank the occurrence of the following malignant tumors.

SCC; MM; FSA; OSA

How does this contrast with the UC Davis data?

A
  • This study:
  1. SCC 7%
  2. FSA 6%
  3. MM 4%
  4. OSA 4%
  • Davis Data
  1. SCC & MM 7%
  2. FSA 2%
  3. OSA 2%
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14
Q

Kipp Wingo JVD 2018 #1

what are predisposing factors identified for oral malignant melanoma?

A

Males, cocker spaniels and heavily pigmented dogs predisposed

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15
Q

Kipp Wingo JVD 2018 #1

What is the reported most common intraoral location for a POF, and what breed is predisposed?

A

Rostral maxilla (47%) - this is from Fiani article, site not reported in Wingo.

Boxer

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16
Q

Kipp Wingo JVD 2018 #1

What is the reported most common location for a CAA?

A

Rostral mandible (41%) - this is from the fiani article, site not reported in Wingo

17
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What were the 3 most common lesions and proportion?

A

CAA 45%

POF 31%

FFH 16%

18
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What was the proportion of CAA?

Where were the % in each location?

A

45% of biopsies

Rostral mandible 41%

Caudal mandible 29%

Rostral maxilla 24%

caudal maxilla 6%

19
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What breed predispositions were associated with CAA?

A

Golden retriever, Akita, Cocker, Shetland sheepdog

20
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What was the odds ratio for CAA mandible versus maxilla?

A

2.3

21
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What was the proportion of POF?

A

31%

22
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What were the proportion of POF in each location?

A

Rostral Maxilla 47%

Caudal mandible 21%

rostral mandible = caudal maxilla = 16%

23
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What breed predeliction was found for POF? What sex predilection?

A

overrepresented in castrated males. no breed in this study.

24
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

What was the odds ratio for POF for maxilla versus mandible?

A

1.7

25
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

what was the proportion of FFH in the study?

A

16%

26
Q

According to Fiani N, Verstraete FJM, Kass PH, Cox DP.

Clinicopathologic characterization of odontogenic tumors and focal fibrous hyperplasia in dogs: 152 cases (1995 2005). Journal of the American Veterinary Medical Association. 2011;238(4):495 500.

what were the location prevalences for FFH?

A

Rostral maxilla - 57%

Rostral mandible - 22%

caudal mandible - 17%

caudal Maxilla - 4%

27
Q

What was the proportion of POF in Fiani, Wingo and Svendenius?

A

Fiani - 31%

Wingo - 18%

Svendius - 21%

28
Q

What was the proportion of FFH/gingival hyperplasia/inflammatory in Fiani, Wingo and Svendenius?

A

FIani - 16% (FFH)

Wingo - 28% (inflamamtory)

Svendius - 24% (GH)

29
Q

What was the proportion of CAA in Fiani, Wingo and Svendenius?

A

Fiani - 45 %

Wingo - 14 %

Svendius - 4 %

30
Q

What was the proportion of benign tumors in Wingo and Svendenius?

A

Wingo - 34%

Svendenius - 27%

31
Q

What was the proportion of malignant tumors in Wingo and Svendenius?

A

Wingo - 37%

Svendenius - 15%