Oral Anatomy & Histology (Review: Outcome 3) Flashcards
Embryology
“Embryo-“ relates to early development stages of an animal
“-ology” a science or branch of knowledge
- Important background to understanding how head and neck structures develop
- Understanding normal development allows us to:
i. differentiate normal vs. abnormal appearances
ii. plan for the best possible treatment(s)
Congenital malformations
Developmental disturbances or defects evident at birth
- can be due to:
i. genetic factors (i.e. chromosome abnormalities)
ii. environmental agents and factors (i.e. infections, drugs, and radiation = TERATOGENS)
Embryo vs. Fetus
Similarities:
- developing young of an animal in a womb
Differences:
i. Embryo
- first 8 weeks of development
- structures are not easily recognizable
ii. Fetus
- development period after embryo stage
- structures are more easily recognizable
Embryonic Germ Layers
Week 3
- Endoderm
- inside tube (primitive gut) - Mesoderm
- middle - Ectoderm
- outside tube
Opening at both ends of the tube:
1. Mouth (cephalic/head)
2. Anus (caudal/tail)
Endoderm
- Most internal germ layer
- forms the lining of the stomach, pharynx, and other internal organs
Ectoderm
- Most exterior germ layer
- forms skin, lining of oral cavity, tooth enamel, nervous system, and other external tissues
Mesoderm
- Middle germ layer
- forms muscle, skeletal system, circulatory system, dentin, pulp, cementum
Cleft lip
Unfused area of the upper lip
- fusion of upper lip should occur around week 6
- Cause: failure to fuse one or both maxillary processes with median nasal process
- usually unilateral
- Appearance: absence of center and adjacent lip
- Nose often mis-shaped on affected side
Cleft palate
Unfused areas of a palate
- fusion should occur between week 8-12
- Causes: improper or complete failure to fuse premaxillary area with lateral palatine processes (palatal shelves)
Epithelial Rests
Misplaced groups of epithelial cells
- cells from ectoderm germ layer
- found between embryonic processes fusing together
- causes formation of cysts (group of epithelial cells divided and form a sac) - cysts can grow and distort tissues including teeth
Odontoma
An anomaly or tumor relating to teeth
- benign
- made up of all or some of the tissues that develop into teeth
- two general types:
i. compound (resembles a tooth)
ii. complex (does not resemble a normal tooth)
Nasolabial cyst
A cyst in soft tissue where the upper lip meets the nasal ala
Brachial Cleft Cyst
- Congenital epithelial cysts, which arise on the lateral part of the neck
- a failure of the destruction of the second branchial cleft in embryonic development