Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

A level Physics > Option - Medical Physics > Flashcards

Option - Medical Physics Flashcards

You may prefer our related Brainscape-certified flashcards:
Physics 101 flashcards AP® Physics flashcards
1
Q

what are x-rays?

A

high energy electromagnetic waves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what can x-rays do?

A

ionise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what can x-rays do since they can ionise?

A

they can cause mutations and cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

how are x-rays produced?

A

by descelerating electrons and when electrons drop to inner energy levels of atoms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

how do x-rays tend to travel?

A

in straight lines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what are x-rays absorbed by?

A

dense matter or high atomic number elemtns

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what do x-rays tend to pass through?

A

soft tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what can x-rays be detected by?

A

photographic plates/film

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how are the majority of x-rays produced and how is this done?

A

by descelerating electrons, which require accelerating in order to attain high speeds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

how are electrons accelerated in order to attain high speeds?

A

by using pds of around 50kV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

explain in detail how the x-ray machine/x-ray tube works

A

the hot wire on the left of the diagram is heated using a small pd across the wire (using tungsten as the hot wire means that temperatures of 3400 degrees can be achieved)
this is such a high tempertaures that a small % of the electrons gain eenough energy to escape the hot wire
these electrons are then accelerated using a very large pd of around 50kV between the hot wire and the target (-ve electrons are attractived to the +ve metal target)
the electrons descelerate when they hit the metal target
descelerating electrons produce x-rays
fast electrons also knock out inner electrons from the metal target (atoms are ionised)
electrons from higher energy levels drop down to the gaps left (very big jump if electrons were knocked from lower levels in the atom = big photon)
these falling electrons produce x-rays of very specific wavelength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what do electrons that stop immediately produce?

A

a photon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what’s important about a photon?

A

max energy, minimum wavelength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

2 methods of x-ray production

A

descleerating electrons
electrons dropping to inner levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what do the methods of x-ray production lead to?

A

a distinctive x-ray spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what are the 2 lines to label on an x-ray specrum?

A

line spectrum
continuous spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what are along the axes of an x-ray spectrum?

A

x = wavelength
y = spectral intensity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what causes the line spectrum on the x-ray spectrum?

A

electrons being knocked out of inner levels and outer electrons falling a big energy gap to fill the holes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what causes the continuous spectrum on an x-ray spectrum?

A

electrons slowing down as they strike the target

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

which parts of an x-ray spectrum is the line spectrum?

A

the peaks

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

which parts of an x-ray spectrum is the continuous spectrum?

A

the flat lines

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what does a bigger voltage lead to in terms of light?

A

bigger voltage = higher intensity of lighth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

how do we obtain a higher intensity of light?

A

bigger voltage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

what does an x-ray spectrum show?

A

a line spectrum superimposed on a continuous spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

what happens to most energetic electrons in one strike and what does this cause?

A

lose all of their energy
causes the shortest possible wavelength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

what are x-rays produced in?

A

an x-ray machine/x-ray tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

what does a graph of intensity against wavelength show?

A

a wide continuous spectrum with narrow spikes superimposed on it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

what do we call the narrow spikes on the x-ray spectrum?

A

the line spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

what do the narrow spikes on the line spectrum of the x-ray spectrum correspond to?

A

transitions of electrons down to lower energy levels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

what leads to the narrow spikes of the line spectrum?

A

the energy levels of the electrons are at very specific energies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

what is the line spectrum very similar to?

A

the emission spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

what will a 60kV spectrum always have that’s higher than a 50kV spectrum?

A

a higher intensity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

what happens to the minimum wavelength as the tube pd increases in the x-ray tube?

A

minimum wavelength decreases

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

do the positions of the spikes in the line spectrum change?

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

how do we change the positions of the spikes in the line spectra?

A

by changing the metal of the target

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

what will changing the metal of the target in the x-ray tube do to the line spectrum?

A

change the positions of the spikes in the line spectra

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

how come we can calculate the highest energy x-rays?

A

because no x-ray can have more energy than the incoming electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

what can an x-ray not have more energy than?

A

the incoming electrons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

if an electron (by some incredibly coincidence) loses all its energy in only one collision with the metal target, which energies will be the same?

A

the energy of the x-ray photon produced will be the same as the energy of the electron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

when will the energy of the x-ray photon produced be the same as the energy of the electron?

A

if the electron loses all its energy in only one collision with the metal target

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

equation for the highest energy x-rays + explain

A

hfmax = eV
hf max = the maximum energy of the photon
eV = the energy of the electron

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

give the full equation for the highest energy x-rays and explain

A

hfmax = eV
using c = flambda, we can replace fmax with fmax = c/lambdamin giving

hc/lambda min = eV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

what is the equation for the highest energy x-rays almost identical to?

A

the equation used for photons from an LED

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

why is the equation for the highest energy x-rays almost identical to the equation for photons from an LED?

A

they both arise from
electron potential energy (eV) = photon energy (hf)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

photon energy

A

hf

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

electron potential energy

A

eV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

hf

A

photon energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

eV

A

electron potential energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

what is the intensity of x-rays proportional to?

A

the current in the x-ray tube

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

what is proprtional to the current in the x-ray tube?

A

the intensity of the x-rays

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

how can the current in the x-ray tube be varied?

A

by alternating the temperature of the hot wire (absorbers and filters can be used too)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

what’s bad about the process of changing the current in an x-ray tube by altering the tempature of a hot wire?

A

it’s very inefficient - most of the input energy ends up as wasted heat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

how do we work out the speed of electrons?

A

KE of electrons = initital PE of electrons

1/2mv^2 = eV

(m = mass of an electron, which is in the data book)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

what happens to the intensity of x-rays as they pass through a medium?

A

their intensity decreases exponentially according to:

I = Ioe^(μx)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

equation for the exponential decrease of x-ray intensity as they pass through a medium

A

I = Ioe^(μx)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

I = Ioe^(μx) + explain the symbols

A

equation for the exponential decrease of x-ray intensity as they pass through a medium

I = intensity of the x-rays
I0 = original intensity of the x-rays
μ = absorption (or attenuation) coefficient
x = distance travelled by the x-rays

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

what is the half value thickness for x-ray absorption given by?

A

x1/2 = ln2/μ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

what is half value thickness?

A

the thickness that gives half the x-ray intensity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

state and explain what the half value thickness equation is

A

the half value thickness is the thickness that gives half the x-ray intensity
i.e –> I/I0 = 1/2 hence 1/2 = e^(-μx1/2)
taking logs of both sides gives

ln (1/2) = -μx1/2 –> ln (2) = μx1/2

—-> x1/2 = ln2/μ

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

which fact is image intensification based on?

A

the fact that a 30kV x-ray photon has 10,000x more energy than a 3eV visible photon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

what do we use to absorb x-rays?

A

crystals called scintillators

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

what do crystals called scintillators do?

A

absorb x-rays

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

what do scintillators do once they’ve absorbed x-rays?

A

they convert the energy of one x-ray into multiple visible photons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

why is it good that scintillators convert the energy of one x-ray into multiple, visible photons?

A

it’s a lot easier to detect these visible photons than it is to detect one x-ray photon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

what has happened when a scintillator has converted the energy of one x-ray into multiple visible photons?

A

the image is intensified

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

disadvantage of x-ray techniques

A

the exposure to ionising radiation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

why is image intensification important?

A

it can reduce x-ray dosages by factors of between 50 and 1200

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

efficiency

A

output energy/input energy x100

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

give 2 examples of image intensification

A

the x-ray cassette
fluoroscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

describe the x-ray cassette

A

2 outer layers = scintillators
centre “filling” = the photographic plate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

what happens to most of the x-rays in the first scintillator in an x-ray cassette?

A

they pass straight through

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

what happens when we place a second scintillator on the opposite side of the plate in an x-ray cassette?

A

we can almost double the exposure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

what does image intensification lead to in terms of x-ray dosage?

A

it means that the x-ray dosage for an x-ray is reduced by a factor of between 50 and 1200, depending on the resolution required for the image

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

what’s good and bad about thicker scintillators?

A

provide more intensification but they also blur the image

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

what type of x-rays provide moving images of the patient’s inwards?

A

fluoroscopy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

what does fluoroscopy do?

A

provides moving images of the patient’s inwards

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

explain exactly how fluoroscopy is done

A

the tube and collimater ensure we have a directed beam of x-rays
the x-ray filter gives us a beam with a suitable mean wavelength
the anti-scatter grid is similar to the collimator. it’s a group of hollow cylinder making sure that we only detect x-rays travelling in the correct direction (we don’t want x-rays that have been scattered in the wrong direction because they will blur the image)
the image is produced in the sctintullator screen with each absorbed x-ray giving around 1000 visible photons
the CCD video camera continually sends images of the screen to a monitor for the surgeon to carry out the operation
the scintillator and CCD camera are both kept in a dark container - we only want to detect light from the scintillator screen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

what does an x-ray filter do?

A

gives us a beam with a suitable mean wavelength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

what is an anti-scatter grid and what does ti do?

A

a group of hollow culinders maling sure that we only detect x-rays travelling in the corect direction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

why don’t we want x-rays travelling in the wrong direction?

A

they will blur the image

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

another disadvantage to x-ray imaging in addition to the exposure to ionising radiation

A

the low contrast between soft tissues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

how can the low contrast between soft-tissues in x-ray imaging be overcome?

A

with the use of contrast media

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

contrast medium

A

a substance that includes a high atomic number element for increase x-ray absorption

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
84
Q

2 most common contrast media

A

barium metal
iodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
85
Q

explain how and why barium metal is a common contrast medium to use in x-ray imaging

A

this is uually barium sulfate mixed with water which is swallowed by the patient. Barium, having an atomic number of 56, is a good absorber of x-rays and assists greatly in taking images of all areas of the alimentary canal (throat, stomach, small intestine etc)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
86
Q

explain how and why iodine is a common contrast medium to use in x-ray imaging

A

liquids containing iodine can be injected into veins or arteries leading to pictures or even videos of blood flow. iodine has an atomic number of 53 which provides the extra absorption and contrast required for these images

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
87
Q

CT scan

A

an x-ray image that utilises a fan shaped beam opposite a line of digital detectors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
88
Q

an x-ray image that utilises a fan shaped beam opposite a line of digital detectors

A

CT scan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
89
Q

how are the beam and detectors rotated around the patient during a CT scan?

A

in a helical pattern

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
90
Q

what happens when the beam and detectors are rotated around the patient in a helical pattern during a CT scan?

A

it takes multiple “slices” of the patient to produce a 3D image

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
91
Q

advantages of a CT scan over a normal x-ray image

A

it produces 3D images
it produces better soft-tissue contrast

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
92
Q

disadvantages of CT scans

A

it requires a greater x-ray dosage
it is more expensive and can take longer for a detailed scan although a quick torso scan takes around 10 seconds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
93
Q

explain how radiotherapy is done

A

a beam of high energy x-rays are directed towards the tumour
the beam is then rotated around the patients with the tumour at the centre of rotation - this means that the tumour recieved the maximum dose while the dose to the surrounding tissue is kept as low as possible

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
94
Q

what is the photon energy range usually used for x-ray imaging?

A

20kev - 150keV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
95
Q

what is the imaging x-rays usual half value thickness?

A

around 5cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
96
Q

what do we require to be higher for radiotherapu?

A

we need more penetrating x-rays that have higher half value thicknesses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
97
Q

what is the range of radiotherapy photons usually?

A

1meV to 25MeV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
98
Q

half value thicknesses of radiotherapy photons

A

10-50cm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
99
Q

what do higher energies of the x-rays used for radiotherpy ensure?

A

that whole tumours can be irradicated reasonably uniformly

100
Q

how come whole tumours can be irradicated reasonably uniformly during radiotherapy?

A

higher energies of the x-rays used

101
Q

what are easier to kill - cancer cells or healthy cells?

A

cancer cells

102
Q

what’s the problem with the high energy x-ray doses used in radiotherpy?

A

they can cause secondary cancers (the risk of secondary cancers is approximately 10% after 25 years have passed)

103
Q

absorbed dose symbol and equation

A

D = total energy of radioation absorbed/mass

104
Q

absorbed dose (D) unit

A

Gy (gray) or Jkg-1

105
Q

what does equivalent dose also take into account?

A

the relative danger of the radiation itself

106
Q

equivalent dose symbol and equation (+explain)

A

equivalent dose is very similar to the absorbed dose however it also takes into account the relative danger of the radiation itself
H = DWR
WR = radiation weighting factor

107
Q

when is Wr usually 1?

A

for x-rays and gamma rays and for beta radiation

108
Q

WR for alpha radiation

A

20

109
Q

how do we know that alpha radiation is 20x more dangerous than other radiations?

A

noramally WR = 1 for x-rays and gamma rays and beta radiation
WR = 20 for alpha radiation

110
Q

effective dose equation + explanation

A

effective dose is also very similar to the absorbed dose however it takes into account both the relative danger of the radiation itself (WR) and the realtive dange to the tissue (WT)
WT = tissue weighting factor

E = HWT
combining with H equation for equivalent dose:

E = DWRWT

111
Q

effective dose unit

A

Sv

112
Q

what does WT vary from and for what?

A

varies from 0.01 for skin, brain and bone surface to 0.12 for lungs, colon and bone marrow
so, irradiating the lungs is 12x more dangerous than irradiating the skin

113
Q

how do we know that irradiating the lungs is 12x more dangerous than irradiating the skin?

A

WT is 0.12 for the lungs and 0.01 for the skin

114
Q

which effect do we rely on to produce and detect ultrasound?

A

the piozoelectric affect

115
Q

what does the piozoelectric effect allow us to do?

A

produce and detect ultrasound

116
Q

piozoelectric effect

A

physical deformation causes a voltage and vice versa

117
Q

what happens to the piozoelectric crystal when a pd is applied?

A

it deforms

118
Q

when does a piozoelectric crystal deform?

A

when a pd is applied

119
Q

explain how ultrasound pulses are produced in a probe

A

a high frequency (2-15MHz) alternating pd is sent to the electrodes.
the reverse piozoelectric effect means that the crystal will deform at the same frequency producing ultrasound waves of the required frequency (2-15MHz)
when the ultrasound pulses are reflected from whatever is being analysed, they arrive back at the piozoelectric crystal. this time, the sound waves will deform the piozoelectric crystal and the piozoelectric effect mmeans that an alternating pd will be defelected across the electrodes
the absorber block and acoustic insulation help improve the quality and direction of the pulses by stopping reflections and absorbing waves going in the wrong direction
the plastic nose is designed to have the correct acoustic impendance for maximum trasmission and might even incorporate a lens to focus the ultrasound beam

120
Q

what does an absorber block and acoustic insulation in a probe that produces and detects ultrasound do?

A

helps improve the quality and direction of the pulses by stopping reflections and absorbing waves going in the wrong direction

121
Q

how is the plastic nose in a probe that produces and detects ultrasound designed?

A

to have the correct acoustic impendance for maximum transmission and might even incorporate a lens to focus the ultrasound beam

122
Q

how many detectors do A scans have?

A

only one

123
Q

what happens in an A scan?

A

an ultrasound pulse is sent and a series of reflections is received

124
Q

what can be done with an A scan and how?

A

in an A scan, an ultrasound pulse is sent and a series of reflections is received.
various time-delays are then used to measure various distances

125
Q

common use of an A-scan

A

to scan the eye for a detached retina or to check the thickness of the lens before an operation (the scan can be done with the eye closed)

126
Q

how do we calculate time delays in A scans?

A

remember to double the thickness of a lens for example when the pulse is reflected back and passes through a second time
use the general std triangle

127
Q

describe the probe used for B scans

A

the prove has multiple ultrasound emitters (each of which is a detector when the pulse is reflected back)

128
Q

how many emitters is it common for ultrasound probes to have and what can these then do?

A

512
these can produce a line image that is 512 dots (or pixels) wide

128
Q

how do you obtain a 2D image from a B scan?

A

the emitters produce a line image and when the probe is rotated, a 2D image is produced by joining many of these line images together

129
Q

common use of B scans

A

imaging foetuses

130
Q

acoustic impendance equation + define symbols

A

Z = cp
c = speed of sound in the material
p = density of the material

131
Q

what is it that gives us reflections of ultrasound?

A

diffeences in acoustic impendance

132
Q

what do differences in acoustic impendance give us for ultrasound?

A

reflections

133
Q

what is the fraction of ultrasound reflected at a boundary between two materials (R) with acoustic impendance Z1 and Z2 given by?

A

R = (Z2 -Z1)^2/(Z2 + Z1)^2

134
Q

if our reflection coefficient (R) is 1, what does this mean?

A

nothing is transmitted (All reflected)

135
Q

when do we know that nothing is transmitted and that all of the ultrasound is reflected in terms of the reflection coefficient?

A

if its 1, nothing is tranmitted

136
Q

what do we need to consider when we use the doppler shift to measure the speed of blood flow?

A

reflection and angles

137
Q

how do we measure the speed of blood flow?

A

using the doppler shift

138
Q

how do we consider the velocity of flow when working out the speed of blood flow?

A

as a component in the direction of the ultrasound waves

139
Q

what 3 things do we need to consider when measuring the speed of bloof flow?

A

consider the velocity of flow as a component in the direction of the ultrasound waves
consider that the waves encountered by red blood cells will be squashed
the red blood cells, when they reflect, are also moving sources

140
Q

equation for the doppler shift to work out the speed of blood flow

A

deltaf/fo = 2v/c costheta
or
-deltalambda/lambdao = 2v/c x costheta

141
Q

MRI

A

magnetic resonance imaging

142
Q

what is magnetic resonance imaging based on?

A

the spin of hydrogen nuclei (protons)

143
Q

how come there are plenty of hydrogen nuclei in our bodies for an MRI scan?

A

our bodies contain 75% water (H2O) and so there are plenty of hydrogen nuclei in our bodies to assist the MRI scan

144
Q

what do all spinning charges have?

A

magnetic fields

145
Q

how come a hydrogen nucleus is a tiny magnet?

A

all spinning charges have magnetic fields

146
Q

what happens when we apply a B field to a hydrogen nucleus?

A

the hydrogen nuclei tend to align in the same direction as the applied B -field (As any magnet would)

147
Q

what do hydrogen nuclei do in addition to aligning in the same direction as the applied B-field?

A

precess around the direction of the applied B-field

148
Q

what can happen to a hydrogen atom if its gains enough energy?

A

it can flip to a higher energy state where its own magnetic field is in the opposite direction to the applied field (but it still precesses)

149
Q

what does the frequency at which the hydrogen nuclei precess depend on?

A

the applied B field

150
Q

equation for the frequency at which the hydrogen nuclei precess + name

A

f = 42.6x10^6B
larmor frequency

151
Q

larmor frequency

A

the frequency at which the hydrogen nuclei precess
f = 42.6x10^6B

152
Q

what would happen if we sent radio waves at the hydrogen nuclei at the larmor frequency? how about when we remove the radiowaves?

A

resonance will occur and many hydrogen nuclei will flip the the higher energy state (opposite B-field orientation)
removed –> the nuclei gradually will flip back to align with the B-field

153
Q

what do hydrogen nuclei do when they flip back to align with the B field after removing the applied radiowaves?

A

the hydrogen nuclei emit radiowaves at the same frequency when they flip back. these radio waves are detected to produce the MRI image

154
Q

what’s different in terms of different tissues for an MRI scan?

A

different tissues take a different characteristic time to flip back and this is the main reason that MRI gives good contrast for different soft tissue

155
Q

why does an MRI scan give good contrast for different soft tissue?

A

because different tissues take a different characteristic time to flip back

156
Q

what is the “flipping back” time of protons usually called?

A

the “relaxation time”

157
Q

how can we produce multiple MRI images to build a 3D scan?

A

we can image one slice at a time

158
Q

how do we image one slice at a time during an MRI scan to build a 3D scan?

A

by having a B-field that varies from head to toe

159
Q

explain how having a B-field that varies from head to toe helps to build a 3D MRI scan

A

as the B-field varies from head to toe, we can “tune in” to different slices of the body by varying the frequency of the radiowaves. only the slice with the correct resosance frequent will respnod to the radio waves and only that slice will be imaged.

160
Q

what does PET stand for?

A

positron emission tomography

161
Q

what is a PET scan based on?

A

position-electron annihilation

162
Q

what happens when a position annihilates an electron?

A

two gamma ray photons of energy 0.51MeV are produced

163
Q

how can we check how much energy is released when a position annihilates an electron?

A

using E = mc^2

164
Q

what is the mass lost in the reaction of when a position annihilates an electron and why?

A

the mass of an electron plus the pass of a position (since photons have no mass)

165
Q

compare the mass of an electron to the mass of a position

A

exactly the same

166
Q

why is the mass lost in the annihilation of an electron by a position equal to 2 electron masses?

A

since a position has the exact same mass as an electron

167
Q

J to eV

A

divide

168
Q

eV to J

A

multiply

169
Q

why is the energy released during positron-electron annihilation always divided equally between the 2 photons?

A

because of the conservation of momentum - the initial momentym of the position and electron is always negligible so that the momentum of the two photons must cancel

170
Q

what do we do when performing a PET scan?

A

enclose the area being scanned by a ring of gamma detectors

171
Q

when do we know that position-electron annihilation has taken place in a PET scan?

A

when two photons are detected almost simultaneously

172
Q

how do we work out exactly where positron-electron annihilation took place during a PET scan?

A

when two photons are detected almost simultaneously, we know that a position-electron annihilation has taken place
we also know that the annihilation took place somewhere on the line between the two detectors
the gamma detectors can measure time delays of around 1ps and this means they know where along the line annihilation took place

173
Q

what can gamma detectors do during a PET scan?

A

can measure time delays of around 1ps and this means they know where along the line annihilation took place

174
Q

what can be done after completing a PET scan?

A

a 3D image of annihation hotspots can be build by using a computer and averaging over time

175
Q

how would we do a calculation to work out where during a PET scan annihilation took place?

A

distance = velocity x time
use 3x10^8 as velocity and the time given

176
Q

how do we get the positions for a PET scan inside the patient in the first place?

A

use fluorine-18 as the beta+ emitter

177
Q

why don’t we need to supply annihilating electrons for a PET scan?

A

because there are plenty of those in the body already

178
Q

show how fluorine-18 is a beta+ emitter

A

18F9 –> 18O8 + +1B + Ve

179
Q

half life of fluorine-18?

A

110 minutes

180
Q

how must fluorine-18 be produced?

A

using a cyclotron

181
Q

why are PET scans not available in small hospitals?

A

require fluorine-18 for beta+ to be emitted, and fluorine-18 must be produced using a cyclotron

182
Q

what must you do once fluorine-18 has been produced?

A

must react it (chemically) quickly to produce a glucose (called Fluorodeoxyglucose, FCG)

183
Q

what is done to the glucose formed from fluorine-18?

A

it’s injected into a vein where it travels to the parts of the body that use it

184
Q

how come hotspots appear in a PET scan?

A

the glucose from the beta+ emittiing fluorine-18 is used by the cancers since cancers require a lot of energy and glucose

185
Q
A
186
Q

How is blood volume calculated? describe the method

A

By injecting a radioactive chemical into the patients blood
You then wait 10 to 20 minutes for the tracer to mix uniformly throughout the patient’s blood.
Then, a small amount of blood is obtained from the patent (around 10cm^3)
The activity of this 10cm^3 sample can be used to calculate the total volume of the patient’s blood

187
Q

What do we assume when calculating blood volume?

A

That the activity is the same throughout the time period

188
Q

Total volume of blood equation

A

Activity of tracer x sample of blood taken/activity of sample

189
Q

Radioactive tracers

A

Radioactive chemicals which are put inside a patient (either injected or ingested)

190
Q

What must radioactive tracers for imaging do?

A

Emit body-penetrating gamma rays that can be viewed by a gamma camera outside the body

191
Q

What should the half life of a radioactive tracer be and why?

A

A few hours
Long enough to take an image but short enough not to give a large radioactive dose to the patient

192
Q

Most common radioactive tracer

A

Technetium-99m

193
Q

Explain why technetium-99m is a commonly used radioactive tracer

A

It has a half life of 6 hours and emits gamma rays

194
Q

Why is technetium-99m only produced in specialised hospitals?

A

Requires a cyclotron

195
Q

Collimator

A

A collection of hollow lead tubes

196
Q

A collection of hollow lead tubes

A

Collimator

197
Q

What will Collimator do?

A

Only collect rays moving vertically upward

198
Q

What does a scintillator counter count?

A

Electric pulses

199
Q

Explain how images are produced using technetium-99m and a gamma camera

A

The patient will be emitting gamma rays in all directions, so we need a Collimator to collect only the rays moving vertically upward
The gamma rays are absorbed by the scintillator which produces approximately 4000 light photons for each incident gamma ray - a large 2D network of photomultiplier tubes provide an electric pulse each time light is detected in front of them
The scintillator counter counts these pulses and passes the information to a computer which displays a 2D image on the screen

200
Q

Does a computer have to do anything clever to produce an image using technetium-99m and a gamma camera? Explain

A

Unlike CT, MRI and PET, no.
It merely reproduced the faint image that appears on the scintillator

201
Q

What type of cameras can be set up to view the image on a scintillator?

A

Sensitive CCD cameras (similar to the set up for fluoroscopy)

202
Q

How do the images using technetium-99m and a gamma camera tend to come out and why?

A

Low resolution
The Collimator tubes have to be quite thick to absorb the misdirected gamma rays

203
Q

For the imaging technique ultrasound, explain its…
Radiation exposure
Application
Biological effects
Cost
Conditions
3D imaging
Definition
When not to use

A

No ionising radiation
Generally soft tissue including foetus, skeletal joints
No known hazards in imaging
Low cost
Short time, usually painless
Usually 2D images
Not high - depends on the skill of the practitioner
Always safe. Not usually suitable for lung imaging but used for collapsed lung

204
Q

For the imaging technique standard x-ray explain its…
Radiation exposure
Application
Biological effects
Cost
Conditions
3D imaging
Definition
When not to use

A

Varying but usually low exposure to ionising radiation
Mainly bone breakages, with contrast agent can also be used for soft tissue
Carcinogenic effects and developmental defects in embryos
Low cost
Very short time
Usually 2D images
High definition of bony structures
Pregnancy

205
Q

For the imaging technique CT scan explain its…
Radiation exposure
Application
Biological effects
Cost
Conditions
3D imaging
Definition
When not to use

A

Higher exposure to ionising radiation (0.02 - 10m5v) up to 5 years background
Bone injuries, lung and chest imaging, cancer detection, A&E investigations
Carcinogenic effects and developmental defects in embryos
About 1/2 the cost of MRI
Quite a short time (5 min), ideally no movement but less of a problem than MRI
Yes, using a helical scan
High definition of bony structures, moderate definition of soft structure
Pregnancy. Weight limit of about 200kg because of space and strength of moving table

206
Q

For the imaging technique MRI, explain its…
Radiation exposure
Application
Biological effects
Cost
Conditions
3D imaging
Definition
When not to use

A

No ionising radiation
All kinds of soft tissue imaging e.g brain, injuries, tumours
No known hazards
High cos
Long time, uncomfortable (no movement allowed), noisy, claustrophobic
Yes
High definition (but requires a stationary subject)
Some mental implants, heart pacemakers. Weight limit about 150kg due to the space and strength of the table

207
Q

What does the metal filter do in an x-ray machine?

A

Produced a beam of x-rays of suitable wavelength
Absorbs low energy x-rays so they’re not absorbed by the tissue, causing damage

208
Q

How do we work out the force exerted by an electron beam on a target?

A

F = mv x no. of electrons per second

209
Q

How do we work out the number of electrons per second?

A

Q/charge of an electron

210
Q

Disadvantages of a PET scan

A

Expensive
Low resolution

211
Q

Why would an ultrasound B scan not work for detecting a cancerous tumour in a person’s lung?

A

Too much air reflection

212
Q

Another use of radioactive tracers

A

Blood flow through the brain check for blockages

213
Q

Equation to work out the minimum wavelength on an x-ray spectrum

A

Minimum wavelength = hc/E

214
Q

How to work out energy from voltage

A

E =Ve

215
Q

Describe how the Doppler shift principle can be used to measure the speed of blood through an artery

A

Pulse sent by transducer at an angle to the blood vessel
Pulse reflected by moving blood cells
Pulse detected by transducer
Speed calculated using the Doppler shift of the ultrasound

216
Q

Give all of the properties of technetium-99m that make it a good radioisotope in the effective diagnosis of medical problems

A

Emits gamma rays which penetrate through the skin and so are detectable outside of the body
Half life of 6 hours —> long enough to take an image but short enough not to give a large radioactive dose to the patient
Daughter products are stable
Low ionisation

217
Q

Dose unit

A

Sv

218
Q

How do we get larger photon energies (x rays)?

A

Greater pd

219
Q

What does a greater pd mean in terms of photon energies?

A

Greater photon energies

220
Q

When will we get an ultrasound echo in terms of acoustic impedance? Explain

A

Acoustic impedance is significantly different in both materials = will reflect = ultrasound echo

221
Q

What happens when acoustic impedance is significantly different in both matters? Explain

A

Will reflect = ultrasound echo

222
Q

What do we call the light photons produced by a scintillator?

A

Scintillations

223
Q

What should be equal in a PET scan and why?

A

Mass-energy of electron should be equal to the photon energy because 2e —> 2 gamma ray photons

224
Q

Would MRI image soft tissue?

A

Yes

225
Q

Would MRI provide moving images?

A

No

226
Q

What does a greater current do for an x ray?

A

Greater intensity

227
Q

How do we get a greater intensity (x ray)?

A

Greater current

228
Q

What does a greater pd do in an x ray?

A

Larger photon energies

229
Q

How do we get larger photon energies in an x ray?

A

Greater pd

230
Q

How come x-rays are absorbed by bones?

A

They are absorbed by dense matter or high atomic number elements (not penetrated)

231
Q

What are x rays if they’re not absorbed by something?

A

Penetrated

232
Q

Why do we need a vacuum between the heater and the tungsten target in an x-ray tube?

A

To avoid collisions on the way to the target

233
Q

What do we need to remember to do for speed of blood flow questions?

A

Use c from the question - not from the data book!

234
Q

Are contrast media used for ct scans?

A

Yes

235
Q

Where do radioactive tracers go?

A

To hyperactive parts to locate problem areas

236
Q

What do we need to be careful with in x-ray absorption questions?

A

Be careful when a question says reduced intensity by 60% for example - the new intensity is 40% not 60%

237
Q

Key word for when describing piezoelectric crystals

A

The crystal vibrates

238
Q

What kind of images can B-scans generate?

A

2D
Moving images

239
Q

What do we need to do at the end of the calculation when working out the thickness of fat using acoustic impedance and why?

A

Distance divided by 2
Since the ultrasound pulse has travelled through the source and back again over this distance, so the thickness is half of this

240
Q

What do we do when we have a question about efficiency and the rate of production of heat?

A

Use P= IV

241
Q

Why can’t we have the wavelength of x-rays as zero?

A

Voltage/energy would have to be infinite

242
Q

What type of voltage is needed for the piezoelectric effect to produce ultrasound?

A

Alternating, high frequency

243
Q

What type of voltage is needed for the piezoelectric effect to produce ultrasound?

A

Alternating, high frequency

244
Q

Which of these is in real time and which isn’t - CT scan, x-ray

A

CT scan = real time
x-ray = not real time

A level Physics (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions