Optical Isomers pt2 Flashcards
Physical Properties of Optical Isomers
- A pair of optical isomers have identical physical properties such as melting point, boiling point, solubility etc.
Physical Properties of Optical Isomers
- A pair of optical isomers have identical physical properties such as melting point, boiling point, solubility etc.
how do you distinguish optical isomers ?
- Optical isomers rotate the plane of polarised light with equal magnitude, but in opposite directions
what instrument is used to measure optical activity ?
a polarimeter
what kind of waves is plane polarised light composed by ?
of waves that vibrate in only one plane.
what kind of waves is plane polarised light composed by ?
of waves that vibrate in only one plane.
what does the polarimeter consist of?
- A light source (usually a sodium lamp)
- A polarising filter
- A sample cell for the optically active substance
- An analyser
- A scale for measuring the degree of rotation
what does the polarimeter consist of?
- A light source (usually a sodium lamp)
- A polarising filter
- A sample cell for the optically active substance
- An analyser
- A scale for measuring the degree of rotation
what is a polarimeter ?
a device for measuring the optical rotation of a chiral compound using plane-polarised light.
A chiral compound that rotates the plane of light clockwise is called……
dextrorotatory (+)
A chiral compound that rotates the plane of light counterclockwise is called………….
levorotatory (-)
what is specific rotation ?
a standardised value that is obtained from the measured optical rotation.
A 50:50 mixture of a pair of optical isomers is known as…….
a racemic mixture
Pharmaceutical Example of Optical Isomers
Ibuprofen
- the anti-inflammatory activity is due to the S form.
- The R form of ibuprofen can actually slow down the beneficial effect of the active optical isomer.
example of Sensory Perceptions of Optical Isomers
Limoene
- Our taste buds and scent receptors are chiral in nature.
- Thus, we are able to distinguish between the different taste of pairs of optical isomers
+Limonene found in oranges
- Limonene found IN LEMONS
