Optic Nerve Anomalies - Acquired Flashcards

1
Q

What is papilloedema?

A

•Papilloedema is a swelling of the ON secondary to raised intra-cranial pressure

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2
Q

Is papilloedema unilateral or bilateral?

A

•Papilloedema is typically bilateral but may be asymmetric

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3
Q

What is the managment for papilloedema?

A

•Any patient presenting with papilloedema should be suspected of having an intracranial mass and referred immediately

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4
Q

What are the symptoms associated with papilloedema?

A
  • VA not affected initially but increase in size of blind spot as progresses
  • Blurred vision – transient when rising to stand
  • Double vision (VIth nerve palsy)
  • May have RAPD
  • Headaches – worse after lying down - this is a big indication
  • Nausea
  • Vomiting
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5
Q

What does early papilloedema look like?

A
  • Mild disc swelling and hyperaemia - nasal margins affected first
  • Blurring of disc margins
  • Venous engorgement (i.e. veins getting bigger is the first sign)
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6
Q

What may established papilloedema present with?

A
  • Disc swelling
  • Cotton wool spots
  • Retinal folds
  • Hard exudates
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7
Q

What is atrophy?

A

The wasting away or deterioration of something

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8
Q

What are symptoms and signs of optic atrophy?

A
  • Progressive loss of vision
  • Colour Vision, VF and VA all affected
  • Disc appears pale
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9
Q

What are the two types of optic atrophy- describe each one.

A

Primary and Secondary

•Primary

  • This is optic atrophy that is not associated with another disease
  • It is often hereditary - (most common is Leber’s hereditary optic neuropathy – loss of vision in one eye or both in teens or twenties)

•Secondary

  • Associated with another disease
  • Usually Alcohol/tobacco or Drug induced.
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10
Q

What is the management of Optic Atrophy?

A
  • It is Irreversible
  • If not noted previously then referral to HES – speed depends on VA and whether progressive or not (from patient’s symptoms)
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11
Q

What may optic neuritis be caused by?

A
  • Optic neuritis is caused by inflammation, infection or demyelination of the optic nerve
  • Para-infectious causes may occur due to a viral infection or immunisation
  • Infectious causes may be due to syphilis, lyme disease and cat-scratch fever
  • Can be idiopathic
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12
Q

What is the most common cause of optic neuritis?

A

Demyelination as a result of a disease such as Multiple Sclerosis

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13
Q

What is multiple sclerosis (MS)?

A
  • Multiple Sclerosis (MS) is a disease of the central nervous system where there is demyelination of the nerve fibres
  • Demyelination can occur anywhere in the body causing neural and muscular impairments which can be mild or severe
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14
Q

Whom does optic neuritis most commonly affect?

A

•Patients usually present between the ages of 20 and 40 – majority are female (3:1)

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15
Q

What is optic neuritis often refered to as and why?

A

•As ON appears normal - condition sometimes referred to as ‘retrobulbar neuritis’

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16
Q

What is the managment of optic neuritis?

A
  • Recovery begins within 2-3 weeks – maximal after 6 months
  • 75% recover VA of 6/9 or better
  • disease associated with relapses - so you have to keep an eye on the px
  • Treatment may delay further relapses
  • Refer – soon if due to demyelination
17
Q

What is an infarct?

A

A small localized area of dead tissue resulting from failure of blood supply.

18
Q

What is Anterior Ischaemic Optic Neuropathy and hwo does it occur?

A

It is an Infarct of the ONH – tissue death due to inadequate nerve supply.

It is due to an occlusion of the short posterior ciliary arteries

19
Q

What visual field loss is anterior ischaemic optic neuropathy associated with?

A

Associated with altitudinal hemianopia

20
Q

What is the visual prognosis of someone with anterior ischaemic optic neuropathy?

A

Visual prognosis is poor and VA/VF loss is permanent

21
Q

What are the two types of Anterior Ischaemic Optic Neuropathy (AION) and whom are they most common in?

A
  • Non-arteritic – NAION (not associated with arteritis) is more common more likely to occur in younger individuals
  • Arteritic - AAOIN (associated with arteritis) is more likely to occur in older individuals
22
Q

What are the symptoms associated with Non-Arteritic Anterior Ischaemic Optic Neuropathy?

A

Patients present with severe, painless, sudden loss of vision

23
Q

What are the signs of Non-arteritic Anterior Ischaemic Optic Neuropathy?

A
  • Pale swollen disc
  • Surrounding haemorrhages
24
Q

What is Non-arteritic Anterior Ischaemic Optic Neuropathy associated with?

A
  • ‘At risk’ discs – small or absent cup – crowded disc – in conjunction with with hyperopia
  • Impaired circulation as opposed to inflammation so could be due to (i) hypertension or (ii) diabetes or (iii) high cholesterol levels
25
Q

What is the managment for Non-Arteritic Ischaemic Optic Neuropathy?

A
  • No treatment possible
  • 30% lose vision in other eye within two years
  • Refer to casualty – arteritis (and so arteritic Anterior Ischaemic Optic Neuropathy) needs to be excluded
26
Q

What is so concerning about Arteritic Anterior Ischaemic Optic Neuropathy?

A

It is a sight and life threatening condition

27
Q

What may arteritic Anterior Ischaemic Optic Neuropathy also be called?

A

Can be referred to as Giant Cell Arteritis (GCA)/Temporal arteritis

28
Q

What is Arteritic Anterior Ischaemic Optic Neuropathy caused by?

A

•Caused by inflammation of the small and medium arteries around the ONH – especially the temporal, ophthalmic and posterior ciliary arteries.

29
Q

What are symptoms of Artertic Anterior Ischaemic Optic Neuropathy?

A
  • Sudden profound painless unilateral loss of vision
  • Age usually between 60 to 80 years
  • Jaw claudication
  • Scalp tenderness
  • Temporal headache
  • Tender inflamed nodular arteries – can see in the picture
  • Weight loss
  • Fever night sweats
  • Might experience TIA (Transient Ischaemic Attacks)
30
Q

What is the management for Arteritic Anterior Ischaemic Optic Neuropathy?

A
  • Following immediate referral patients - temporal artery biopsy and bloods taken – check for raised erythrocyte sedimentation rate (ESR) check to confirm diagnosis
  • High dose steroid required to decrease inflammation (this is done even without confirmed diagnosis just incase px does have the arteritic kind)
  • High dose of steroid Can help to preserve sight in the remaining eye even though VA in affected eye does not recover
  • Steroids also reduce risk of cerebral vascular accident
31
Q

True or False- 2/3rds of px with optic neuritis will show a normal fundus

A

True