opthamology Flashcards

1
Q

How do you differentiate posterior vitreous detachment, retinal detachement and vitreous haemorrhage?

A

Posterior vitreous detachment:
Flashes of light/ floaters in peripheral vision.
Fundoscopy- Weiss ring
visualacuity normal
No emergency mx - will settle by self

Retinal detachment:
Same sx as vitreous detachment (flashers and floaters)
A veil over the field of vision
Straight lines appear curved.
Shadow in peripheray, progressing towards middle (as retina peels off orbit)
Central visual loss.
Fundoscopy - retinal tear, ‘tobacco dust’ in anterior chamber

Vitreous haemorrhage:
Large bleeds cause sudden visual loss.
Moderate bleeds may be described as numerous dark spots.
Small bleeds may cause floaters.
Occurs when blood leaks into the vitreous humour from damaged blood vessels in conditions such as diabetic retinopathy or retinal tears or from anti-cogulants/ bleeding disorders.

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2
Q

How do you differentiate central retinal vein occlusion from central retinal arterial occlusion?

A

Both cause painless visual loss

Retinal vein: more common, with age, can be caused by glaucoma, hypertension, polycythaemia.
Starts subtle then progresses to full loss
optic disc swelling, and multiple flame-shaped and blot haemorrhages may be seen.
occurs when there is a blockage in the central retinal vein, leading to impaired venous drainage from the retina. This results in increased pressure within the blood vessels, causing them to leak blood and fluid into the surrounding tissues.

Retinal arterial: SUDDEN blindness. Cherry spot on pale retina on fundoscopy, afferent pupillary defect,

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3
Q

When blood vessel is affected in ischaemic optic neuropathy?

A

due to occlusion of the short posterior ciliary arteries, causing damage to the optic nerve

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4
Q

Anterior uveitis vs acute closed angle glacuoma signs and sx?

A

Acute closed-angle glaucoma:
sudden unilateral eye pain and visual loss.
Haloes around lights.
Poor vision in dark.
headache.
erythematous globe with a fixed and DILATED pupil with a hazy cornea.
Can be brought on my mydriatic activity eg drops/ watching TV

Anterior uveitis (AKA iritis):
painful red eye with photophobia.
hypopyon
ciliary flush
Vairable visual loss.
CONSTRICTED pupil.
HLA-B27/ autoimmune association

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5
Q

What is keratitis?

A

microbial invasion of the cornea causing eye redness, gritty foreign sensation type pain, photophobia, increased lacrimation, corenal haziness and eyelid oedema.
can get hypopyon if severe

RF: trauma and contact lens

Emergency - topical antibiotic eye drop/ PO abx if bad

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6
Q

What is retinitis pigmentosa? What do u see on fundoscopy?

A

inherited retinal disorders
Cause progressive degeneration of the retina, leading to night blindness and peripheral vision loss (tunnel vision)
fundoscopy shows black bone spicule-shaped pigmentation in the peripheral retina and mottling of the retinal pigment epithelium

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7
Q

What does fundoscopy for diabetic retinopathy show?

A

Usually slow onset visual loss.

Fundoscopy shows microaneurysms, dot and blot haemorrhages, hard exudates, and cotton wool spots (retinal arterial obstrution causing ischaemia)

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8
Q

What is Argyll-Robertson pupil

A

small, irregular pupils
no response to light but there is a response to accommodate
Associated with neurosyphilis but most common cause in UK is DM

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9
Q

What is a stye vs chalazion vs blepharitis?

A

stye (hordeolum externum): infection of the glands of the eyelids. PAINFUL

A chalazion (Meibomian cyst) is a retention cyst of the Meibomian gland. PAINL\ESS lump normally the internal eyelid.

blepharitis: inflammation of the eyelid margins typically leading to a red eye

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10
Q

How do you manage a stye?

A

management includes hot compresses and analgesia. CKS only recommend topical antibiotics if there is an associated conjunctivitis

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11
Q

What is a holmes- adie pupil?

A

Tonically dilated pupil, slowly reactive to light with more definite accommodation response. Caused by damage to parasympathetic innervation of the eye due to viral or bacterial infection. Commonly seen in females, accompanied by absent knee or ankle jerks.
80& time is unilateral

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12
Q

What is a marcus-gunn pupil?

A

AKA Relative afferent pupillary defect, seen during the swinging light examination of pupil response. The pupils constrict less and therefore appear to dilate when a light is swung from unaffected to affected eye. Most commonly caused by damage to the optic nerve or severe retinal disease.

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13
Q

What is horners syndrome?

A

Miosis (pupillary constriction), ptosis (droopy eyelid), apparent enophthalmos (inset eyeball), with or without anhidrosis (decreased sweating) occurring on one side. Caused by damage to the sympathetic trunk on the same side as the symptoms, due to trauma, compression, infection, ischaemia or many others.

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14
Q

What is hutchinsons sign?

A

Unilaterally dilated pupil which is unresponsive to light. A result of compression of the occulomotor nerve of the same side, by an intracranial mass (e.g. tumour, haematoma)

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15
Q

What is open-angle glaucoma ? How does it present? RF? findings on exam?

A

Glaucoma = raised intraocular pressure
Open angle = peripheral iris is NOT covering trabecular meshwork –> aqueous humor can drain

RF: age, fhx, myopia, HTN, DM, steroids

Presentation: insidious, peripoheral visual field loss (nasal scotoma), decreased acuity

Fundoscopy:
1. Optic disc cupping - cup-to-disc ratio >0.7 (normal = 0.4-0.7), occurs as loss of disc substance makes optic cup widen and deepen
2. Optic disc pallor - indicating optic atrophy
3. Bayonetting of vessels - vessels have breaks as they disappear into the deep cup and re-appear at the base
4. Additional features - Cup notching (usually inferior where vessels enter disc), Disc haemorrhages

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16
Q

How does dry vs wet age related macular degeneration present?

A

BOTH: blurred central vision and poor vision at night. Patients often complain that straight lines become curved.

Dry: Drusen (small accumulations of extracellular material between Bruch’s membrane and the retinal pigment epithelium of the eye,) on opthalmoscopy, comes on gradual
Nothing can be done for this

wet: faster, choroidal neovascularisation on opthalmoscopy

anti-VGEF injections for wet ARMD - urgent referral to opthamology needed

17
Q

How does hypertensive retinopathy present sx + signs with diff stages?

A

Hypertensive retinopathy is often asymptomatic but can present with reduced acuity.

Stage 1: Mild narrowing of the arterioles + silver wiring
Stage 2: Focal constriction of blood vessels and AV nicking
Stage 3: Cotton-wool patches, exudates and haemorrhages
Stage 4: Papilloedema

First they start to twist and turn [silver wiring], then they nip about the place [AV nipping], afterwards they play with cotton wool and fire [cotton wool spots, flame and blot haemorrhages], finally they swell up [papilloedema].

18
Q

How do cataracts present?

A

Cataracts are often asymptomatic if they aren’t in the visual axis. If they do present with symptoms it is generally a loss of vision with problems such as haloes due to light scattering. A peripheral cataract can easily be visualised on slit lamp examination, and there would be no optic disc involvement.

19
Q

Describe chorioretinitis and its fundoscopy appearance

A

Infection/ autoimmune disease leads to inflammation of chroid and retina
COMMONLY caused by CMV so need to check for underlying HIV
Causes blurred vision, loss and floaters.
Pizza pie appearance on fundoscope - retinal spots (superficial retinal infarction + flame-shaped haemorrhages

20
Q

Describe endophthalmitis?

A

inflammation of the intraocular fluids (vitreous and aqueous) usually post op

Sx: Red eye, pain and visual loss following intraocular surgery are red flags for endophthalmitis - need urgent ophthalmic review

21
Q

entropion vs ectropion?

A

entropion: in-turning of the eyelids
ectropion: out-turning of the eyelids

22
Q

Mx of acute glaucoma

A

Administer pilocarpine, timolol, and brimonidine eye drops

definitive mx = laser peripheral iridotomy

23
Q

What anaesthetic eye drops should you give for a corneal ulcer?

A

Prescribing anaesthetic eye drops for patients with corneal ulcer is not advisable as it may cause more harm- delays healing of the ulcer

24
Q

Mx of anterior uveitis?

A

steroid + cycloplegic (mydriatic) drops

25
Q

What is the most common long term complication of cataract surgery?

A

Posterior capsule opacification often happens years after cataract surgery and is often the most common cause of blurring of vision years after cataract surgery. Once a cataract surgery is done, it is impossible to get a recurrence of cataract because the lens has already been replaced with an artificial lens.

26
Q

What are the stages of diabetic retinopathy?

A

Background – microaneurysms, retinal haemorrhages, hard exudates and cotton wool spots
Pre-proliferative – venous beading, multiple blot haemorrhages and intraretinal microvascular abnormality (IMRA)
Proliferative – neovascularisation (most important - is why is proliferative) and vitreous haemorrhage

27
Q

What is first line for primary open angle glaucoma?

A

Latanoprost (PG analogue)

28
Q

How do you treat herpes zoster opthamalicus vs herpes simplex keratitis?

A

Herpes zoster Ophthalmicus-Oral aciclovir + topical steroid
Herpes simplex keraTiTis- Topical aciclovir

29
Q

what is Diabetic maculopathy

A

Diabetic maculopathy describes any structural abnormality due to diabetes affecting the macula