Opioid Pharma Flashcards

1
Q

Endogenous opioids

A

endorphins
enkephalins
dynorphins
endomorphins

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2
Q

μ (MOP) RECEPTOR STIMULATOR

for analgesic and reward

A

β-endorphin
endomorphin-1
endomorphin-2

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3
Q

OPIUM

A

morphine
codeine (analgesic and antitussive)
thebaine (semisynthetic ligands)

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4
Q

EXOGENOUS OPIOIDS

A
heroin
oxycodone
meperidine
pentazocine
hydromorphone
hydrocodone
buprenorphine
synthetics are methadone and LAAM (levy-alpha-acetylmethadol)
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5
Q

HEROIN

A

IV 1/2 life 3 minutes, for 6-MAM 30 minutes

IM, IV, intranasal have heroin and 6MAM peaks within 5 minutes

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