Opioid Pharma Flashcards
1
Q
Endogenous opioids
A
endorphins
enkephalins
dynorphins
endomorphins
2
Q
μ (MOP) RECEPTOR STIMULATOR
for analgesic and reward
A
β-endorphin
endomorphin-1
endomorphin-2
3
Q
OPIUM
A
morphine
codeine (analgesic and antitussive)
thebaine (semisynthetic ligands)
4
Q
EXOGENOUS OPIOIDS
A
heroin oxycodone meperidine pentazocine hydromorphone hydrocodone buprenorphine synthetics are methadone and LAAM (levy-alpha-acetylmethadol)
5
Q
HEROIN
A
IV 1/2 life 3 minutes, for 6-MAM 30 minutes
IM, IV, intranasal have heroin and 6MAM peaks within 5 minutes