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ASAM Essentials Addiction Medicine > Neurobiology of Addiction > Flashcards

Neurobiology of Addiction Flashcards

1
Q

% GENETIC VULNERABILITY ADDICTION

A

40-60%

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2
Q

TREATING COMORBIDITIES paradigm, eg HIV

A

Seek Test Treat Retain

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3
Q

DOMAINS OF DYSFUNCTION ADDICTION CYCLE

A

binge/intoxication (incentive salience)
withdrawal/negative affect (negative emotional states)
preoccupation/anticipation (executive function)

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4
Q

BINGE/INTOXICATION SITE

A

basal ganglia

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5
Q

WITHDRAWAL/NEGATIVE AFFECT SITE

A

extended amygdala

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6
Q

PREOCCUPATION/ANTICIPATION

A

prefrontal cortex

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7
Q

NEUROTRANSMITTER MEDIATES STRESSOR RESPONSE

A

corticotropin releasing factor

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8
Q

NICOTINE RECEPTORS

A

nicotinic

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9
Q

ALCOHOL RECEPTORS

A

γ-aminobutyric acid

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10
Q

OPIOID RECEPTORS

A

opioid

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11
Q

MARIJUANA RECEPTORS

A

cannabinoid (predominantly CB1)

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ASAM Essentials Addiction Medicine (17 decks)

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