Only UW perinatal Hepatitis B 04-02 (2)

Question 1

UW table. epidemiology

90 proc. risk of vertical transmission without prophylaxis

<2 proc. risk after prophylaxis

Chronic infection in 90 proc. of perinatally infected infants

Answer 1

.

Question 2

UW table. Risk factors? 2

Answer 2

High maternal viral load
Maternal HBeAg+

Question 3

UW table. Transmission. 3

Answer 3

Perinatal exposure to genital secretions (most common)
Transplacental (rare)
NOT TRASMITTED BY BREASTFEEDING

Question 4

UW table. prevention? 2

Answer 4

HBV vaccine (active immunization)
AND
HBIG (passive immunization)

Question 5

UW. Newborns of all mothers with active HBV should be passively immunized at birth with hepatitis B immune globulin (HBIG), followed by active immunization with recombinant HBV vaccine. These should be administered within 12 hours of birth, regardless of the infant’s birth weight or clinical condition.

Answer 5

.

Question 6

UW. Active (HBV vaccine) or passive (HBIG) immunization alone does not provide suitable protection against vertical transmission. Vaccine and immune globulin should always be given together as prophylaxis against HBV for newborns of HBsAg+ mothers.

Question 7

UW. Obtaining the infant’s serologic status or liver function testing is unnecessary before administering prophylaxis.

Question 8

UW. HBV infection is not transmitted through breast milk; HIV is the only absolute infectious contraindication to breastfeeding in the developed world. Because this mother is HIV-negative, breastfeeding should be encouraged.

Answer 8

.