Ondansetron Flashcards
1
Q
Ondansetron - Mechanism of action
A
Is an antiemetic.
Blocks serotonin receptors in the brain and GI tract, resulting in reduction in nausea and vomiting.
Metabolised in the liver.
2
Q
Ondansetron - Indications
A
Clinically significant nausea and/or vomiting.
3
Q
Ondansetron - Contraindications
A
Known severe allergy.
Age less than 1 year.
4
Q
Ondansetron - Cautions
A
None
5
Q
Ondansetron - Dosage
A
4mg IM for adult if IV access cannot be obtained.
See paediatric drug table for child doses.
6
Q
Ondansetron - Common side effects
A
Headache.
Flushing.
7
Q
Ondansetron - Onset of effect
A
5-10 minutes for IM
8
Q
Ondansetron - Duration of effect
A
4 - 8 hours.
9
Q
Ondansetron - Preparation
A
Ampoule containing 4mg in 2ml
Ampoule containing 8mg in 4ml
10
Q
Ondansetron - Repeats
A
May be repeated after 20 minutes if required.
