Ondansetron

Question 1

What class of medication is Ondansetron?

Answer 1

Antiemetic/Serotonin antagonist

Question 2

What is the MOA of Ondansetron?

Answer 2

Blocks serotonin receptors in the Chemoreceptor trigger zone (CTZ), the stomach, and the small intestine

Question 3

What are the indications for giving Ondansetron?

Answer 3

Nausea and Vomiting

Question 4

What is the onset time for Ondansetron?

Answer 4

10-30 minutes

Question 5

What is the duration time for Ondansetron?

Answer 5

Peak: 2 hours

Question 6

What are the contraindications for giving Ondansetron?

Answer 6

Known hypersensitivity

Question 7

What are the side effects of Ondansetron?

Answer 7

Headache, lightheadedness, constipation
May cause QT interval elongation which increases the chance of torsade de pointes

Question 8

What is the trade name of Ondansetron?

Answer 8

Zofran

Question 9

What is the dose of Ondansetron given?

Answer 9

4-8mg

Question 10

By which route is Ondansetron given?

Answer 10

ODT, IV, IM