Naloxone

Question 1

What class of medication is Naloxone?

Answer 1

Narcotic Antagonist

Question 2

What is the MOA of Naloxone?

Answer 2

Naloxone is chemically similar to narcotics, but it only has antagonist properties. Competes for opiate receptors in the brain. Also displaces narcotic molecules from opiate receptors. Can reverse respiratory depression associated with narcotic overdose.

Question 3

What are the indications for giving Naloxone?

Answer 3

Used for the complete or partial reversal of depression caused by narcotics.

Question 4

What is the onset time for Naloxone?

Answer 4

<2 minutes IV/IO
2-10 minutes IM/IN

Question 5

What is the duration time for Naloxone?

Answer 5

Peak: Variable
Total: 30 minutes

Question 6

What are the contraindications for giving Naloxone?

Answer 6

Hypersensitivity

Question 7

What are the side effects of Naloxone?

Answer 7

Should be administered cautiously to patients known or suspectedly to be physically dependent on narcotics. Can cause withdrawal-type effects

Question 8

What is the trade name of Naloxone?

Answer 8

Narcan

Question 9

What is the dose of Naloxone given?

Answer 9

1-2mg IV, IO, IN
Can also be administered via SVM

Question 10

By which route is Naloxone given?

Answer 10

IV,IN, IM