Oncology (cancer) Flashcards
oncos
benign tumor, slow growth, encapsulated
carcinos
malignant tumor, fast growth, invasive/infiltrative, anaplastic, metastatic
neoplasm
tumor의 다른 명칭
주변조직 침범여부에 따른 분류 3가지
encapsulated(피막형성), invasive(침습성), infiltrative(침윤성)
invasive와 infiltrative 차이
invasive: enter and destroy surrounding tissue
infiltrative: extending beyond normal tissue boundaries
morphology 용어 2가지
anaplasia(역형성의), hyperchromatic(과다염색의)
location 용어 1가지
metastatic(전이)
발암유발 인자 2가지
environmental agents, heredity
environmental agents 종류 3가지
chemical carcinogens, radiation, oncogenic viruses
chemical carcinogens 종류 3가지
hydrocarbons, hormones, insecticides
oncogene 뜻 및 4가지
종양유전자, RAS(colon cancer), ABL(chronic myelogenous leukemia), MYC(lymphoma), PML-RARA
heredity 특징 및 종류 4가지
tumor suppresor genes, BRCA(ovarian, breast), APC(polyposis coli syndrome), p53(Li-fraumeni, 최빈), Rb1(retinoblastoma, 최초발견)
oncogene vs TSG
oncogene = gain of function, TSG = loss of function
cancerous tumors 분류 기준
histogenesis(조직발생)의 기원 세포 종류
cancerous tumors 3가지 및 유래조직
carcinoma(epithelial), sarcoma(connective), mixed-tissue tumors(미분화 세포, 특히 줄기세포)
carcinoma 2가지
adenoma(샘종, 양성), adenocarcinoma(샘암종, 악성)
sarcoma 유래 조직의 3가지 이름
기원: mesodermal layer(중배엽)
구성: mesenchymal tissue(중간엽 조직)
역할: parenchyme(실질)
sarcoma 7가지
osteosarcoma, osteoma, leukemia, lymphoma, giloma, neuroblastoma, rhabadomyosarcoma
mixed-tissue tumor 2가지와 위치
Wilms tumor (kidney), Teratoma (ovaries, testes)
pathologic description 2가지와 경우
gross(클 때), microscopic(작을 때)
gross description 7가지
cystic, fungating, inflammatory, medullary, necrotic, polypoidy, ulcerating
cystic 2가지
mucinous(점액성), serous(장액성)
fungating
버섯 모양의
polypoidy
폴립 모양
microscopic description 10가지
alveolar, carcinoma in situ, diffuse, dysplastic, epidermoid, follicular, papillary, pleomorphic, scirrhous, undifferentiated
alevolar
꽈리의
carcinoma in situ
상피내암종, 그 자리에 그냥 있는 것
diffuse
spreading evenly throughout
dysplastic
형성이상