Oncology Flashcards

1
Q

Factors improving prognosis of cancers

A
  • early diagnosis
  • careful investigation
  • accurate staging of extent
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2
Q

Red flags in the diagnosis of childhood cancers

A
  • purpura and pallor
  • lymphadenopathy
  • any unexplained mass
  • prolonged fever and lassiture
  • bone pain
  • eye changes
  • unexplained CNS signs
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3
Q

Infectious causes of localised lymphadenopathy

A

Bacterial

  • pyogenic
  • TB

Viral

  • cat scratch
  • rubella
  • EBV
  • HIV

Others

  • toxo
  • histoplasmosis
  • syphillis
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4
Q

Causes of generalised lymphadenopathy

A
  • infections (rubella, EBV, TB, HIV)
  • connective tissue disorders (SLE, JCA)
  • neoplastic (leukaemia, lymphoma)
  • granulomatous disease (sarcoid)
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5
Q

Causes of abdominal masses

A
  • Wilms tumour
  • neuroblastoma (cross midline, ill)
  • B cell non Hodgkin lymphoma
  • sarcomas
  • teratomas
  • germ cell tumours
  • lymphoma
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6
Q

What eye changes are concerning?

A
  • white reflex
  • recent onset squint
  • proptosis
  • loss of vision
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7
Q

Causes of eye changes

A
  • rhabdomyosarcoma
  • neuroblastoma
  • CNS tumour
  • leukaemia
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8
Q

Long term side effects of cancer treatment

A
  • infertility
  • cardiomyopathy
  • learning problems
  • pulmonary fibrosis
  • renal insufficiency
  • deafness
  • growth retardation
  • second malignancy
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