Malaria Flashcards

1
Q

Presenting symptoms of malaria

A
  • fever
  • fast breathing
  • coma and convulsions
  • anaemia
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2
Q

Drug treatment for malaria

A
  • IV Quinine
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3
Q

Drugs used for prophylaxis

A
  • mefloquine
  • doxycycline
  • chloroquine
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4
Q

2 major clinical syndromes of severe malaria

A
  • severe malaria anaemia (parasitaemia and Hb <5)

- cerebral malaria (sustained coma with inability to localise pain)

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5
Q

Characteristics of cerebral malaria

A
  • deep coma
  • recurrent seizures
  • posturing
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6
Q

Aetiology of cerebral malaria

A

Segmentation of parasitised erythrocytes in microvasculature

Decreased deformability of infected red cells

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