Oncology Flashcards

1
Q

What are the 3 broad types of tumour?

A

Epithelial
Mesenchymal
Round cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Features of epithelial type tumours

A

Locally invasive
Metastasise later on
Per-tumoral inflammation
Requires less of a surgical removal area

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Name the 5 epithelial type tumours

A
  1. Papilloma
  2. Squamous cell carcinoma
  3. Transitional cell carcinoma
  4. Adenoma
  5. Adenocarcinoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the characteristics of mesenchymal type tumours?

A

Metastatic
Connective tissue or bone
Ability to spread through blood and seen at a later stage
Surgical treatment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Name the 5 types of mesenchymal type tumour

A
  1. Fibroma/Fibrosarcoma
  2. Osteoma/osteosarcoma
  3. Haemangioma/Hemangiosarcoma
  4. Lipoma/Liposarcoma
  5. Chondroma/ chondrosarcoma
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What group of tumours affect the immune system and respond to chemotherapy well?

A

Round cell tumours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What type of tumour are unpredictable and do what they want?

A

Melanoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the features of a high grade tumour?

A

Higher mitotic count and poorly differentiated with nuclear atypia. Involve necrosis and are locally invasive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is staging?

A

An assessment that combines features of the primary tumour and a measurement of where it has spread

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is maximum tolerated dose chemotherapy?

A

High dose every 3 weeks to treat the cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is maximum tolerated dose chemotherapy?

A

High dose every 3 weeks to treat the cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is metronomic chemotherapy?

A

Giving low dose chemotherapy to modulate the body’s own immune system

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are tyrosine kinase inhibitors used for?

A

Licenced for non-receptible, high grade mast cell tumours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What can be used for neoplasia palliative care?

A

Prednisolone on it’s own if committed and not wanting to pursue chemotherapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What should be included when summarising a tumour?

A

Stage, grade, type, sample method, location

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the grade of a tumour?

A

Features of the tumour on cytology/histopathology which allow predictions to be made about the tumour’s behaviour.

17
Q

What does TNM staging stand for?

A

Tumour, lymph Node, distant Metastasis

18
Q

Describe radial surgery

A

Entire compartment or structure containing mass (limb, muscle, bone)

19
Q

What is curative intent surgery?

A

2-3cm lateral margins and one fascial plane

20
Q

Describe marginal surgery

A

Removing all the mass within the pseudocapsule

21
Q

Describe cytoreductive surgery

A

Removing the bulk of disease within the pseudocapsule

22
Q

How do most chemotherapy drugs work?

A

They affect the cell’s ability to divide by affecting DNA

23
Q

When giving chemotherapy, what is vital to ensure?

A

First stick catheter, appropriate restraint and extravasation

24
Q

Adverse side effect of cyclophosphamide

A

Sterile haemorrhagic cystitis