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usmle > Oncogenes > Flashcards

Oncogenes Flashcards

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USMLE® Step 1 flashcards
1
Q

Alk

A

Receptor tyrosine kinase

Lung adeno Ca

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2
Q

BCR ABL

A

tyrosine kinase t9:22
CML
ALL

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3
Q

Bcl 2

A

Anti apoptotic molecule
Follicular
Diffuse large B cell lymphoma

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4
Q

BRAF

A

Serine/threonine kinase
Melanoma
Non Hodgkin lymphoma
Papillary ca thyroid

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5
Q

Ckit

A

Cytosine receptor

GIST

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6
Q

Cmyc

A 
Transcription factor
Burkitt lymphoma (t 8:14)
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7
Q

Her2/neu

C erb B 2

A

Receptor tyrosine kinase

Breast and gastric ca

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8
Q

JAK2

A

Tyrosine kinase

Chronic myeloproliferative disorders

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9
Q

Kras

A

GTPase
Colon
Lung ca
Pancreatic ca

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10
Q

MYCL1

A

Transcription factor

Lung tumor

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11
Q

MYCN

A

Transcription factor

Neuroblastoma

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12
Q

RET

A

Receptor tyrosine kinase
MEN2a
MEN2b
Medullary ca thyroid

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usmle (24 decks)

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