OM- Salivary Gland Tumours Flashcards
Prevalence of tumours through major glands
Parotid- 80% of all tumours
Sublingual- 80% of all malignant tumours
How do u classify salivary gland tumours
Epithelial neoplasms:benign/malignant
Non-epithelial neoplasms: lymphoma/sarcoma
Salivary gland tumour- major gland: signs
Lump in affected gland
Assymetry
Salivary obstruction
Pain/facial palsy
Salivary gland tumours- minor glands: commonest sites
Junction of hard and soft palate
Upper lip/cheek
Tongue
How do u take a biopsy of a salivary gland tumour for diagnosis
Ultrasound guided fine needle aspiration
Core biopsy
Incisional biopsy
Problems with diagnosing salivary gland tumours
Variation within tumour- complex pathology
Common features between tumours
Not all tumours fit classification
Pleomorphic adenoma tumour features
Most common tumour
Parotid most common
Slow growth
Varied histology-mixed tumour
Tx=excision
Pleomorphic adenoma tumour histology
Incomplete fibrous capsule
Myoepithelial cells
Myxoid tissue
Salivary gland tumour types
Pleomorphic adenoma
Warthin’s tumour
Adenoid cystic carcinoma
Mucoepidermoid carcinoma
Warthin’s tumour features
2nd most common tumour
Parotid most common
Presents bilaterally, in both glands
Tx=excision
Warthin’s tumour histology
Cystic spaces
Distinctive epithelium
Lymphoid tissue
Adenoid cystic carcinoma features
Malignant
Minor salivary glands more common
Presents with dull,continuous pain- infiltrates nerves/bone
Very difficult to remove-infiltrates nerves
Adenoid cystic carcinoma histology
Swiss cheese appearance
Dark stained malignant cells
Cell growth around myelin sheaths
Mucoepidermoid carcinoma features
Malignant
Involves squamous and glandular cells
Unpredictable behaviour- lymphatic spread rare
Possibly intra-osseous
Mucoepidermoid carcinoma histology
Squamous epithelium
Mucous secreting cells
Cystic spaces
