Odontogenesis- EXAM I Flashcards

1
Q

What four components make up the tooth?

A

Enamel, dentin, cementum & pulp

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2
Q

What four components make up the periodontium?

A

Gingiva, periodontal ligament, cementum, alveolar bone proper

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3
Q

List the six stages of tooth development:

A
  1. Initiation
  2. Bud stage
  3. Cap stage
  4. Bell stage
  5. Apposition
  6. Maturation
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4
Q

During the initiation stage of tooth development what occurs?

A

Cellular induction

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5
Q

During the bud stage of tooth development what occurs?

A

Cellular proliferation

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6
Q

During the cap stage of tooth development what occurs?

A

Proliferation, differentiation & morphogenesis

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7
Q

During the bell stage of tooth development what occurs?

A

Proliferation, differentiation & morphogenesis

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8
Q

During the apposition stage of tooth development what occurs?

A

Induction & proliferation

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9
Q

During the maturation stage of tooth development what occurs?

A

Maturation

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10
Q

Plays an instructional role during the pre-tooth bud stage of tooth formation

A

Epithelium (Ectoderm)

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11
Q

What dictates what type of tooth will be formed?

A

Neural crest cells (mesenchyme)

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12
Q

The enamel organ is derived from:

A

Primitive oral ectoderm

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13
Q

What three structures are prominent during the induction stage of tooth development:

A
  1. Oral ectoderm
  2. Neural crest cells
  3. Dental lamina
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14
Q

When does the induction stage of tooth development occur?

A

6th-7th week

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15
Q

During the induction stage when the ectoderm invaginates into the mesenchyme it can now be referred to as:

A

Dental lamina

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16
Q

The dental lamina is separated from the surrounding mesenchyme by a:

A

Basement membrane

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17
Q

When does the bud stage of tooth development occur?

A

8th week

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18
Q

During the bud stage of tooth development the proliferating oral ectoderm makes the transition into:

A

Dental lamina

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19
Q

When does the early cap stage of tooth development take place?

A

9th to 10th week

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20
Q

During the early cap stage, ______ occurs resulting in the creation of buccal vestibule

A

Apoptosis

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21
Q

Help to hold the shape of the enamel organ during the cap stage of tooth development

A

Stellate reticulum

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22
Q

Cells that are still undifferentiated but make their way up into the inner enamel epithelium area

A

Dental papilla

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23
Q

Some of the dental papilla cells will end up becoming:

A

Odontoblasts & pulp

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24
Q

During the cap stage of tooth development what surrounds the enamel organ, inner enamel epithelium & dental papilla

A

Dental follicle

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25
Q

The dental follicle may also be called the:

A

Dental sac

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26
Q

The dental follicle encapsulates the entire enamel organ & will eventually become the:

A

Periodontal ligament, cementum, & alveolar bone

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27
Q

At this stage, all layers of the enamel organ can be differentiated:

A

Bell stage

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28
Q

During the bell stage, the inside of the enamel organ is comprised of:

A

Inner enamel epithelium

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29
Q

During the bell stage, the enamel organ is covered by _____ on the outside

A

Outter enamel epithelium

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30
Q

The double layer of flattened cells on top of the inner enamel epithelium during the bell stage of developement:

A

Stratum intermedium

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31
Q

During the bell stage, the loosely packed cells on the inside of the stratum intermedium:

A

Stellate reticulum

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32
Q

The rounded cells lining the basement membrane, during the bell stage of tooth development:

A

Pre-odontoblasts

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33
Q

The outer enamel epithelium is comprised of _____ cells & serves as _____

A

Cuboidal cells
Protective barrier

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34
Q

The inner enamel epithelium is comprised of ____ cells & differentiates into _____

A

Cuboidal cells
Ameloblasts

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35
Q

The stellate reticulum are ____ shaped ells forming the network inside the ______

A

Star-shaped
Enamel organ

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36
Q

What serves as the supportive function in enamel production:

A

Stellate reticulum & Stratum intermedium

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37
Q

The stratum intermedium is a compressed layer of:

A

Flat cuboidal cells

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38
Q

The dental sac consists of _____ fibers around the _____

A

Collagen
Enamel organ

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39
Q

What will the dental sac eventually differentiate into?

A
  1. Cementum
  2. PDL
  3. Alveolar bone
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40
Q

The cells nearest to the IEE that have basement membrane separation:

A

Dental papilla

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41
Q

The outter cells of the dental papilla differentiate into:

A

Odontoblasts

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42
Q

The inner cells of the dental papilla differentiate into:

A

Pulp tissue

43
Q

During the bell stage of tooth development- at the bottom where the inner & outer epithelium meet form the:

A

Cervical loop

44
Q

During root development, the junction of the outer & inner enamel epithelia:

A

Cervical loop

45
Q

The cervical loop is the site of _____ in the adult tooth

A

Cemento-enamel junction (CEJ)

46
Q

Fusion of the apical extension of the outer & inner enamel epithelia:

A

Hertwig’s epithelial root sheath

47
Q

What determine the outline of the root, dentin & number of roots the tooth will have?

A

Hertwig’s epithelial root sheath

48
Q

Hertwig’s epithelial root sheath is removed before the _____ is laid down

A

Cementum

49
Q

Enamel formation stops at the termination of the:

A

Enamel organ

50
Q

Enamel formation stops at the termination of the enamel organ, but _____ continues & pushes the tooth ______

A

Dentin formation
Occlusally

51
Q

The epithelial diaphragm is the modification of the Hertwig’s sheath creating septa that divide into ____ & create _______

A

Pulpal tissue
Multiple roots

52
Q

Root length is not complete until _______ after the tooth is emerged into the oral cavity

A

1 to 4 years

53
Q

After the tooth is emerged into the oral cavity what happens with the roots?

A

Pulp chamber narrows
Apical opening constricts

54
Q

What type of growth described tooth development?

A

Appositional growth

55
Q

During the apposition stage of tooth development, the stratum intermedium produces:

A

Alkaline phosphatase

56
Q

During the apposition stage the inner enamel epithelium forms _____ which will ultimately form ____

A

Ameloblasts
Enamel

57
Q

During the aposition stage of tooth development the peripheral cells of the dental papillae forms _____ which will ultimately form _____

A

Odontoblasts
Dentin

58
Q

What is the first formed dentin called?

A

Mantle dentin

59
Q

Mantle dentin contains what types of collagen?

A

Type I & III

60
Q

In the mantle dentin, the collagen fiber in the matrix are oriented ____ to the DEJ

A

Perpendicular

61
Q

The presence of the mantle dentin stimulates the:

A

Ameloblasts to secrete enamel matrix

62
Q

During the aposition stage of tooth development the ameloblasts migrate ____ while the odontoblasts migrate ____

A

Ameloblasts- peripherally
Odontoblasts- inward (centrally)

63
Q

Describe actively secreting ameloblasts:

Describe inactive ameloblasts:

A

Tall, columnar cells

Short columnar or elongated cuboidal cells

64
Q

At the final stage of mineralization the reduced ameloblasts with the remaining cells of the outer enamel epithelium, stellate reticulum & stratum intermedium form a membrane on the surface of the enamel. This is termed:

A

Primary cuticle

65
Q

The primary cuticle may also be called:

A

Nasmyth’s membrane

66
Q

What are the four abnormal development categories:

A
  1. Anodontia
  2. Hypodontia
  3. Oligodontia
  4. Hyperdontia
67
Q

Refers to the total lack of tooth development:

A

Anodontia

68
Q

Refers to the lack of development of one or more teeth

A

Hypodontia

69
Q

Refers to the lack of formation of six or more teeth (a subdivision of hypodontia)

A

Oligodontia

70
Q

Refers to the development of an increased number of teeth (the additional teeth are termed supernumerary)

A

Hyperdontia

71
Q

Defect that originates during initiation stage that results in the development of one ore more extra teeth:

A

Supernumerary teeth

72
Q

What stage do supernumerary teeth arise in:

A

Initiation stage

73
Q

The most common manifestation of supernumerary tooth formation:

A

Mesodens

74
Q

Results in multiple small fragments of tooth structure, consisting of dentin, enamel, cementum or any combination, this occurs during the initiation stage

A

Odontoma

75
Q

What stage does odontoma occur in?

A

Initiation stage

76
Q

Comprised of a conglomerate mass of enamel & dentin that bears no anatomic resemblance to a tooth:

A

Complex odontoma

77
Q

Comprised of multiple tooth-like structures:

A

Compound odontoma

78
Q

An enlargement of the body & pulp chamber of multirooted teeth with apical displacement of the bifurcation (for example an exceptionally long root trunk with very short roots):

A

Taurodontism

79
Q

Defined as an abnormal angulation or bend in the root:

A

Dilaceration

80
Q

Defect that originates during Cap stage of development that results in large single-rooted tooth with one pulp cavity & exhibits “twinning” in crown area:

A

Gemination

81
Q

During what stage of tooth development does gemination take place in?

A

Cap stage

82
Q

Tooth count is normal when the double tooth is counted as one in this form of abnormal tooth development:

A

Gemination

83
Q

Refers to a double tooth in which the tooth count reveals a missing tooth when the double tooth is counted as one:

A

Fusion

84
Q

Defect occurring during apposition & maturation stages that results in union of root structure of two or more teeth by cementum:

A

Concresence

85
Q

Defect occurring during cap stage of development that results in an extra cusp due to defects on the enamel organ:

A

Tubercle formation

86
Q

During what stage of tooth development does the concresence occur in?

A

Apposition & maturation stages

87
Q

At what stage of tooth development does tubercle formation occur in?

A

Cap stage

88
Q

Originates by separation of the dental follicle (dental sac) from the crown of an unerupted tooth:

A

Dentigerous cyst (AKA follicular cyst)

89
Q

A dentigerous cyst is attached at the:

A

CEJ

90
Q

Comprises 20% of all jaw cysts:

A

20%

91
Q

Arise from the cells rests of the dental lamina (also called rests of serres)

A

Keratocystic odontogenic tumor

92
Q

The OKC constitutes _____ of all odontogenic cysts

A

3-11%

93
Q

60% of all cases of all odontogenic keratocyst cases are diagnosed in patients between the ages of:

A

10 & 40 years

94
Q

OKCs are considered ______ cysts

A

Bone expanding

95
Q

OCKs located in the posterior mandible often present as:

A

Multilocular lesions

96
Q

What is the treatment choice for an OKC?

A

Surgical removal

97
Q

What occurs 30% of the time following surgical removal of OKCs

A

Recurrence

98
Q

Cyst wall of a keratocystic odontogenic tumor consists of a 6-8 cell layer of stratified squamous epithelium with _____ at the luminal surface

A

Parakeratosis

99
Q

The lumen of an odontogenic keratocyst (OKC) is often filled with:

A

Keratin

100
Q

In an OKC, the presence of inflammation will generally cause epithelial ____ & _____ of the basal cell layer

A

Proliferation
Pallisading

101
Q

The most common neoplastic lesion arising from odontogenic epithelium:

A

Ameloblastoma

102
Q

What type of epithelium does an ameloblastoma arise from?

A

Odontogenic

103
Q

Considered a slow growing, locally invasive tumor that has a multiolocular or “soap bubble” appearance on radiographs:

A

Ameloblastoma

104
Q

Ameloblastomas are ______ when it comes to radiation

A

Radio-resistant