Exam III Questions Flashcards
Name a non-collagenous protein associated with bone:
Osteonectin, osteopontin, osteocalcin, sialoprotein, phosphoprotein, glycoprotein, Bone-specific protein, bone morphogenetic protein, carboxyglutamic acid containing protein
According to your text, which bone morphogenic proteins promotes bone formation?
BMP 2, 4, 6, 7
(if only one can be chosen pick BMP-2)
What compounds are found in bone matrix vesicles
Alkaline phosphatase, pyrophosphatase, glycoprotein, phosphoproteins, phospholipids
_____ is defined as a denuded area of bone that extends through the marginal bone creating a “cleft-like” defect:
Dehiscence
Multiple myeloma accounts for nearly _____ % of all malignancies involving bone
50%
According to your text, the intrinsic fibers of alveolar bone are oriented ____ to the bone surface; the extrinsic fibers of the PDL are oriented ____ to the bone surface
Intrinsic=parallel
Extrinsic=perpendicular
Normally, at 4-5 years of age, the jaws will accomodate a total of _____ erupted and unerupted teeth
20 erupted + 28 developing (unerupted) = 48 teeth total
What is the rate of eruption of teeth?
3 mm every 3 months but this is NOT a constant rate
The deciduous dentition has generally completed eruption by age _____
3 years
Melanocytes are derived from cells of what embryonic structure?
Neural crest
After root formation is complete, the reduced enamel epithelial forms the _____ after eruption
Junctional epithelium
What is the most common neoplastic (cancerous) lesion arising from odontogenic epithelium
Ameloblastoma
Oral cancer accounts for approximately ____% of all cancers
3%
The highest incidence of squamous cell carcinoma is found in which population?
Middle-aged African American males
According to your text, where are oxytalan fibers found?
Periodontal ligament
Oral cancer accounts for approximately ____% of all cancers
3%
Short columnar/Tall cuboidal epithelial cells are found in which ducts?
Striated ducts
What is the classification of the submandibular gland?
Mixed seromucous gland (predominantly serous with mucous contributions)
What is the terminal excretory duct of the submandibular gland?
Wharton’s duct
Pleomorphic adenoma is a benign tumor that accounts for ___% of parotid salivary gland tumors.
53-77%
According to your text, on the posterior slope of the TMJ articular eminence, the inner perpendicular collagen fibers are responsible for ______.
Resting compression of mandibular condyle against the articular surface
In the intimal layer of the TMJ, the macrophage-like cells are the _____.
Type A cells
The Type B synovial cells of the synovial membrane secrete _____.
Hyaluronate
Which receptors are found in the TMJ area?
Ruffini corpuscles - proprioception
Pacinian corpuscles - dynamic mechanoreception
Golgi tendon organs - static mechanoreception
Free nerve endings - pain
2 What is the fibrillar component of the mature dentin matrix?
Type I collagen
2 Histologically, the presence of ____ is used to distinguish the root dentin from the crown dentin.
Tome’s granular layer
2 According to your text, when compared to intertubular dentin, how is peritubular dentin characterized?
It has a greater content of inorganic salts, more mineralized because exposed to more granular stuff
2 During the transition from undifferentiated cell to mature odontoblast, what is the function of fibronectin?
Help align themselves along the basal lamina, assume polarity, and differentiate into secretory cells
2 What is contained in the odontoblastic matrix vesicle?
Alkaline phosphatase, phospholipids, phosphoproteins, pyrophosphatase, calcium, PO4-, Annexin, calcium hydroxyapatite crystallites
2 What growth factors are secreted by the IEE during initiation of odontoblastic differentiation?
- Transforming growth factor (TGF)
- Fibroblast growth factor (FGF)
- Insulin-like growth factor (IGF)
- Bone morphogenetic protein (BMP)
2 What is the function of annexin V in odontoblastic matrix vesicles?
Mediate flow of calcium in to the matrix vesicle; also serves as a collagen receptor that binds matrix vesicles to collagen
2 The theory most commonly accepted to explain why pain is elicited when dentin is mechanically stimulated is the ____ theory?
Brannstrom’s hydrodynamic theory
2 In the dental pulp, macrophages & dendritic cells constitute ___ % of the total cell population
8%
2 The cells responsible for physiologic maintenance of the cementum surface and alveolar bone proper are derived from undifferentiated cells located in the ______
Interstitial spaces of the PDL
2 Where is Tome’s granular layer found?
Dentin of the root adjacent to the cementum
2 A gap between the enamel & cementum at the CEJ has an incidence of occurrence of approximately _____ %
10 %
2 Cementicles are thought to be formed in response to what stimuli?
Response to local trauma or hyperactive occlusion and appear in increasing numbers with increasing age
2 What do teeth look like that exhibit dental erosion?
A- teeth have broad concavities with cupping of occlusal surfaces and dentin exposure
B- Incisal translucency as well as wear on non-occluding surfavecs
C- amalgam restorations appear “raised” and have a non-tarnished appearance
2 A patient with GERD will likely have tooth erosion caused by _____
Stomach acid
2 The thickness of the cementum at the CEJ is approximately _____ micrometers
30-50 micrometers (thinnest here)
2 What is the primary function of cementum?
Provides attachment for the PDL
2 It is thought that nonmyelinated nerve C fibers of the dental pulp are associated with this type of dental pain:
Dull, diffuse pain
2 Most myelinated nerve fibers in the dental pulp are designated as ____ fibers
A-delta
2 It is estimated that each nerve fiber contributes ___ branches to Raschkow’s plexus
8
2 Where do the epithelial rests of Malassez originate from?
Remains of Hertwig’s root sheath
2 An acute pulpal abscess is characterized by dense aggregations of what cell?
Neutrophils & macrophages & other inflammatory cells
2 When a developing carious lesion reaches the DEJ, this will often initiate the formation of what at the pulp interface of the dentin?
Reparative dentin (tertiary dentin)
2 The principle fiber group in the PDL that constitutes the main support of the tooth against masticatory forces is the ____
Obique
2 Which PDL fiber group does NOT exhibit a bony insertion?
Transseptal
2 The “biologic width” is comprised of 1 mm of ____ epithelium and 1 mm of _____
Junction epithelium; gingival fiber ligament (GFL)
2 An aggressive benign tumor derived from odontogenic epithelium that exhibits a radiolucent, multilocular radiographic appearance could be _____
Ameloblastoma
2 The lateral periodontal cyst is through to have its origins in the ____
Epithelial rest of Malassez in the PDL
Leukotrienes, thromboxanes, and prostaglandins all activate Type A cells in the arachidonic acid pathway.
Phospholipids are eassociated with edema, vasodilation & pain in areas of inflammation.
Both statements are true
The initial layer of the TMJ has two types of cells, and the type B cells secrete hyaluronate
True
The left image is a young person’s condylar head
True
Superior lateral pterygoid attaches to the joint capsule & the articular disc. Inferior lateral pterygoid attaches to the neck of the condyle.
Both statements are true
Identify mucocele image
Characteristic of mucocele:
Salivary gland duct is damaged
This image is of a _____
A characteristic of this is ______
Mucocele
Salivary gland duct is damaged
Giant cell tumors cause a painless expansion of bone. Radiographically can be confused with ameloblastoma or periapical cyst.
Both statements are true
The image below shows ______. This can be caused by:
Dehiscence
a. Facial-lingual alignment of teeth
b. Mesial-distal contour of CEJ
c. Facial-lingual width of teeth
d. Presence of enamel pearls or cervical enamel projections
This image shows
Gingival parakeratosis
This image shows:
What is characteristic of this?
Geographical tongue
Filiform with food bolus
Pre-eruptive growth includes:
a. Length of jaw
b. Width of jaw
c. Alveolar ridge height
d. Buccal-lingual width of alveolus
This image shows:
Lichen Planus
Hairy tongue is caused by filiform papillae growth and delayed shedding.
True
These images show:
Benign mucous membrane pemphigoid
This image shows:
Complex odontoma
Complex odontoma defect originates in the initiation stage
True
Bone lining cells=
Inactive osteoblasts that are thought to protect bone from osteoclasts
Dilaceration is thought to be caused by a defect in:
Hertwig’s root sheath
Root is NOT needed for eruption:
True
Identify the medial nasal prominence
Yellow
Taste innervation of the anterior 2/3 of the tongue includes:
CN7-facial nerve
Cleft lip results when there is a lack of fusion between:
Medial nasal and maxillary processes
Mixed gland involved in salivation upon food:
Submandibular gland
Stratum intermedium has cells that alkaline phosphatase. Eventually it is included in the reduced epithelium that forms the junctional epithelium after eruption.
Both statements are true
Metaplasia is a reversible change in which one cell type is replaced by another.
True
Myoepithelial cells associated with acini & secreting stuff from salivary glands
True
Teeth follow the gubernacular canal during eruption. Gubernacular canal contains remnants from dental lamina epithelium.
Both statements are true
When mandible moves, the disc also moves, so all articulation is on the fibrous portion of the disc.
Both statements are true
Characteristic of woven bone:
Collagen randomly oriented
Osteoclasts making environment very acidic to break down hydroxyapatite and then proteins breaking down organic materials.
Both statements are true
Von Ebner’s glands are associated with
Serous only and circumvallate papillae
Choose the false statement regarding the dislocation of the TMJ.
The disc is capable of healing itself quickly
Are deciduous teeth replaced from the buccal or lingual?
Lingual
Vermillion border characteristic:
Blood vessels close to the surface
Tertiary dentin is released immediately in response to outside forces. It is laid down in a clean fashion.
First statement true. Second statement false.
