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Histopathology > Exam III Questions > Flashcards

Exam III Questions Flashcards

1
Q

Name a non-collagenous protein associated with bone:

A

Osteonectin, osteopontin, osteocalcin, sialoprotein, phosphoprotein, glycoprotein, Bone-specific protein, bone morphogenetic protein, carboxyglutamic acid containing protein

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2
Q

According to your text, which bone morphogenic proteins promotes bone formation?

A

BMP 2, 4, 6, 7

(if only one can be chosen pick BMP-2)

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3
Q

What compounds are found in bone matrix vesicles

A

Alkaline phosphatase, pyrophosphatase, glycoprotein, phosphoproteins, phospholipids

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4
Q

_____ is defined as a denuded area of bone that extends through the marginal bone creating a “cleft-like” defect:

A

Dehiscence

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5
Q

Multiple myeloma accounts for nearly _____ % of all malignancies involving bone

A

50%

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6
Q

According to your text, the intrinsic fibers of alveolar bone are oriented ____ to the bone surface; the extrinsic fibers of the PDL are oriented ____ to the bone surface

A

Intrinsic=parallel

Extrinsic=perpendicular

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7
Q

Normally, at 4-5 years of age, the jaws will accomodate a total of _____ erupted and unerupted teeth

A

20 erupted + 28 developing (unerupted) = 48 teeth total

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8
Q

What is the rate of eruption of teeth?

A

3 mm every 3 months but this is NOT a constant rate

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9
Q

The deciduous dentition has generally completed eruption by age _____

A

3 years

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10
Q

Melanocytes are derived from cells of what embryonic structure?

A

Neural crest

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11
Q

After root formation is complete, the reduced enamel epithelial forms the _____ after eruption

A

Junctional epithelium

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12
Q

What is the most common neoplastic (cancerous) lesion arising from odontogenic epithelium

A

Ameloblastoma

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13
Q

Oral cancer accounts for approximately ____% of all cancers

A

3%

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14
Q

The highest incidence of squamous cell carcinoma is found in which population?

A

Middle-aged African American males

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15
Q

According to your text, where are oxytalan fibers found?

A

Periodontal ligament

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16
Q

Oral cancer accounts for approximately ____% of all cancers

A

3%

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17
Q

Short columnar/Tall cuboidal epithelial cells are found in which ducts?

A

Striated ducts

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18
Q

What is the classification of the submandibular gland?

A

Mixed seromucous gland (predominantly serous with mucous contributions)

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19
Q

What is the terminal excretory duct of the submandibular gland?

A

Wharton’s duct

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20
Q

Pleomorphic adenoma is a benign tumor that accounts for ___% of parotid salivary gland tumors.

A

53-77%

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21
Q

According to your text, on the posterior slope of the TMJ articular eminence, the inner perpendicular collagen fibers are responsible for ______.

A

Resting compression of mandibular condyle against the articular surface

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22
Q

In the intimal layer of the TMJ, the macrophage-like cells are the _____.

A

Type A cells

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23
Q

The Type B synovial cells of the synovial membrane secrete _____.

A

Hyaluronate

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24
Q

Which receptors are found in the TMJ area?

A

Ruffini corpuscles - proprioception

Pacinian corpuscles - dynamic mechanoreception

Golgi tendon organs - static mechanoreception

Free nerve endings - pain

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25
Q

2 What is the fibrillar component of the mature dentin matrix?

A

Type I collagen

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26
Q

2 Histologically, the presence of ____ is used to distinguish the root dentin from the crown dentin.

A

Tome’s granular layer

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27
Q

2 According to your text, when compared to intertubular dentin, how is peritubular dentin characterized?

A

It has a greater content of inorganic salts, more mineralized because exposed to more granular stuff

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28
Q

2 During the transition from undifferentiated cell to mature odontoblast, what is the function of fibronectin?

A

Help align themselves along the basal lamina, assume polarity, and differentiate into secretory cells

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29
Q

2 What is contained in the odontoblastic matrix vesicle?

A

Alkaline phosphatase, phospholipids, phosphoproteins, pyrophosphatase, calcium, PO4-, Annexin, calcium hydroxyapatite crystallites

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30
Q

2 What growth factors are secreted by the IEE during initiation of odontoblastic differentiation?

A
  1. Transforming growth factor (TGF)
  2. Fibroblast growth factor (FGF)
  3. Insulin-like growth factor (IGF)
  4. Bone morphogenetic protein (BMP)
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31
Q

2 What is the function of annexin V in odontoblastic matrix vesicles?

A

Mediate flow of calcium in to the matrix vesicle; also serves as a collagen receptor that binds matrix vesicles to collagen

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32
Q

2 The theory most commonly accepted to explain why pain is elicited when dentin is mechanically stimulated is the ____ theory?

A

Brannstrom’s hydrodynamic theory

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33
Q

2 In the dental pulp, macrophages & dendritic cells constitute ___ % of the total cell population

A

8%

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34
Q

2 The cells responsible for physiologic maintenance of the cementum surface and alveolar bone proper are derived from undifferentiated cells located in the ______

A

Interstitial spaces of the PDL

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35
Q

2 Where is Tome’s granular layer found?

A

Dentin of the root adjacent to the cementum

36
Q

2 A gap between the enamel & cementum at the CEJ has an incidence of occurrence of approximately _____ %

A

10 %

37
Q

2 Cementicles are thought to be formed in response to what stimuli?

A

Response to local trauma or hyperactive occlusion and appear in increasing numbers with increasing age

38
Q

2 What do teeth look like that exhibit dental erosion?

A

A- teeth have broad concavities with cupping of occlusal surfaces and dentin exposure

B- Incisal translucency as well as wear on non-occluding surfavecs

C- amalgam restorations appear “raised” and have a non-tarnished appearance

39
Q

2 A patient with GERD will likely have tooth erosion caused by _____

A

Stomach acid

40
Q

2 The thickness of the cementum at the CEJ is approximately _____ micrometers

A

30-50 micrometers (thinnest here)

41
Q

2 What is the primary function of cementum?

A

Provides attachment for the PDL

42
Q

2 It is thought that nonmyelinated nerve C fibers of the dental pulp are associated with this type of dental pain:

A

Dull, diffuse pain

43
Q

2 Most myelinated nerve fibers in the dental pulp are designated as ____ fibers

A

A-delta

44
Q

2 It is estimated that each nerve fiber contributes ___ branches to Raschkow’s plexus

A

8

45
Q

2 Where do the epithelial rests of Malassez originate from?

A

Remains of Hertwig’s root sheath

46
Q

2 An acute pulpal abscess is characterized by dense aggregations of what cell?

A

Neutrophils & macrophages & other inflammatory cells

47
Q

2 When a developing carious lesion reaches the DEJ, this will often initiate the formation of what at the pulp interface of the dentin?

A

Reparative dentin (tertiary dentin)

48
Q

2 The principle fiber group in the PDL that constitutes the main support of the tooth against masticatory forces is the ____

A

Obique

49
Q

2 Which PDL fiber group does NOT exhibit a bony insertion?

A

Transseptal

50
Q

2 The “biologic width” is comprised of 1 mm of ____ epithelium and 1 mm of _____

A

Junction epithelium; gingival fiber ligament (GFL)

51
Q

2 An aggressive benign tumor derived from odontogenic epithelium that exhibits a radiolucent, multilocular radiographic appearance could be _____

A

Ameloblastoma

52
Q

2 The lateral periodontal cyst is through to have its origins in the ____

A

Epithelial rest of Malassez in the PDL

53
Q

Leukotrienes, thromboxanes, and prostaglandins all activate Type A cells in the arachidonic acid pathway.
Phospholipids are eassociated with edema, vasodilation & pain in areas of inflammation.

A

Both statements are true

54
Q

The initial layer of the TMJ has two types of cells, and the type B cells secrete hyaluronate

A

True

55
Q

The left image is a young person’s condylar head

A

True

56
Q

Superior lateral pterygoid attaches to the joint capsule & the articular disc. Inferior lateral pterygoid attaches to the neck of the condyle.

A

Both statements are true

57
Q

Identify mucocele image

Characteristic of mucocele:

A

Salivary gland duct is damaged

58
Q

This image is of a _____

A characteristic of this is ______

A

Mucocele

Salivary gland duct is damaged

59
Q

Giant cell tumors cause a painless expansion of bone. Radiographically can be confused with ameloblastoma or periapical cyst.

A

Both statements are true

60
Q

The image below shows ______. This can be caused by:

A

Dehiscence

a. Facial-lingual alignment of teeth
b. Mesial-distal contour of CEJ
c. Facial-lingual width of teeth
d. Presence of enamel pearls or cervical enamel projections

61
Q

This image shows

A

Gingival parakeratosis

62
Q

This image shows:

What is characteristic of this?

A

Geographical tongue

Filiform with food bolus

63
Q

Pre-eruptive growth includes:

A

a. Length of jaw
b. Width of jaw
c. Alveolar ridge height
d. Buccal-lingual width of alveolus

64
Q

This image shows:

A

Lichen Planus

65
Q

Hairy tongue is caused by filiform papillae growth and delayed shedding.

A

True

66
Q

These images show:

A

Benign mucous membrane pemphigoid

67
Q

This image shows:

A

Complex odontoma

68
Q

Complex odontoma defect originates in the initiation stage

A

True

69
Q

Bone lining cells=

A

Inactive osteoblasts that are thought to protect bone from osteoclasts

70
Q

Dilaceration is thought to be caused by a defect in:

A

Hertwig’s root sheath

71
Q

Root is NOT needed for eruption:

A

True

72
Q

Identify the medial nasal prominence

A

Yellow

73
Q

Taste innervation of the anterior 2/3 of the tongue includes:

A

CN7-facial nerve

74
Q

Cleft lip results when there is a lack of fusion between:

A

Medial nasal and maxillary processes

75
Q

Mixed gland involved in salivation upon food:

A

Submandibular gland

76
Q

Stratum intermedium has cells that alkaline phosphatase. Eventually it is included in the reduced epithelium that forms the junctional epithelium after eruption.

A

Both statements are true

77
Q

Metaplasia is a reversible change in which one cell type is replaced by another.

A

True

78
Q

Myoepithelial cells associated with acini & secreting stuff from salivary glands

A

True

79
Q

Teeth follow the gubernacular canal during eruption. Gubernacular canal contains remnants from dental lamina epithelium.

A

Both statements are true

80
Q

When mandible moves, the disc also moves, so all articulation is on the fibrous portion of the disc.

A

Both statements are true

81
Q

Characteristic of woven bone:

A

Collagen randomly oriented

82
Q

Osteoclasts making environment very acidic to break down hydroxyapatite and then proteins breaking down organic materials.

A

Both statements are true

83
Q

Von Ebner’s glands are associated with

A

Serous only and circumvallate papillae

84
Q

Choose the false statement regarding the dislocation of the TMJ.

A

The disc is capable of healing itself quickly

85
Q

Are deciduous teeth replaced from the buccal or lingual?

A

Lingual

86
Q

Vermillion border characteristic:

A

Blood vessels close to the surface

87
Q

Tertiary dentin is released immediately in response to outside forces. It is laid down in a clean fashion.

A

First statement true. Second statement false.

Histopathology (15 decks)

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