Obstructive Lung Disease Flashcards

1
Q

Obstructive Pulmonary Diseases

A

Diseases of airways, which produce obstruction of expiratory flow

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2
Q

Airflow obstruction can be related to:

A

Retained secretions
Inflammation of mucosal lining of airway walls
Bronchial constriction
Weakening of support structure

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3
Q

Signs of lung hyperinflation

A

Elevation of shoulder girdle
Horizontal ribs
Barrel-shaped thorax
Low, flattened diaphragms

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4
Q

Symptoms

A

Dyspnea on exertion (DOE), especially during functional activities
May have increased anxiety level
Secretion production and cough

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5
Q

COPD – Physical findings

A
Cough/sputum/hemoptysis
Dyspnea – exertion
Decrease breath sounds – more adventitious sounds
Inc RR
Wt loss
Inc AP diameter of chest wall
Cyanosis
Clubbing
Elevated shldr girdle posture
Indications on chest xray
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6
Q

Changes with disease

A

Structural changes to the lung; musculoskeletal changes, psychological component
Lung changes first
Loss of recoil
Rib cage changes shape
As the disease progresses you get a forced expiration instead of passive
Inspiration is affected
Muscle compositions changes

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7
Q

Stage 1 COPD:

A

mild – FEV1 > 80% predicted, with or without chronic symptoms

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8
Q

Stage 2 COPD:

A

mod – 50% < FEV1 < 80%, SOB with exertion

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9
Q

Stage 3 COPD:

A

severe – 30% < FEV1 < 80%, SOB, dec exercise capacity

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10
Q

Stage 4 COPD:

A

very severe - FEV1 < 30%, dec QOL, life threatening

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11
Q

Chronic respiratory failure:

A

FEV1 < 50%

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12
Q

Gold standard for diagnosing COPD

A

spirometry

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13
Q

Lung volumes with COPD:

A

Larger than normal total lung capacity (TLC)

Larger residual volumes (RV)

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14
Q

Adult Obstructive Lung Conditions

A
COPD
Emphysema
Chronic Bronchitis
Combination
Bronchiectasis
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15
Q

Adult COPD

A
easily fatigued 
frequent respiratory infections
use of accessory muscles to breath
orthopneic
cor pulmonale
thin in appearance
wheezing
pursued lip breathing
barrel chest
dyspnea
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16
Q

Emphysema:

A

Condition of lung characterized by destruction of alveolar walls and enlargement of airspaces distal to terminal bronchioles

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17
Q

Chronic Bronchitis

A

Presence of chronic productive cough for 3 months in each of 2 successive years

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18
Q

Pink Puffers

A
emphysema
no bronchitic component
barrel chest
dyspnea early
hunched over
hyperventilation
adequate oxygenation
weight loss
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19
Q

Blue Bloaters

A
chronic bronchitis
bronchitic component cough, mucus
no barrel chest
dyspnea late
no air hunger
ventilation-OK
cyanosis
cor pulmonale
obese
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20
Q

BODE index:

A

body mass, obstruction, dyspnea, exercise, score of 7 to 10 is associated with high mortality rate of 80% in 52 months

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21
Q

Combination COPD – PT Treatment

A
Secretion clearance
Controlled breathing at rest and with activity
Ambulation with rolling walker
Education in use of recovery from SOB positions
Endurance exercise training
Strength training &amp; wt training
Thoracic stretching
Postural reeducation
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22
Q

Bronchiectasis

A

Chronic congenital or acquired disease characterized by abnormal dilatation of the bronchi and excessive sputum production

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23
Q

Bronchiectasis - Symptoms

A

Cough with sputum production (small to large) quantities of mucopurulent secretions
Secretion layers—white frothy, mucoid inner, purulent bottom, composed of thick yellow-green plugs
Sputum greatest in morning
Recurrent, chronic, or recurring lung infections
Hemoptysis

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24
Q

CF:

A

Genetically inherited
Thickening of secretions of all exocrine glands, leading to obstruction (eg. Pancreatic, pulmonary, GI)
CF may present as an obstructive, restrictive or mixed disease

25
Q

Clinical signs of CF:

A

meconium ileus, frequent respiratory infections, especially staphylococcus aureus and pseudomonas aeruginosa and inability to gain weight

26
Q

Symptoms of CF:

A
fatigue
chronic cough
recurrent URI
thick, sticky muscus
chronic hypoxia
clubbing, barrel chest
decreased absorption of vitamins and enzymes
abdominal distention
27
Q

Asthma

A

Trachea & bronchi – inc reaction to stimuli
Reversible – “episodic”
Narrowing of airways
due to inflammation, constriction, secretions
Always some degree of inflammation

28
Q

Asthma - PT Tx

A
Need to have medication regime established first
Secretion clearance
Controlled breathing
Exercise &amp; strength
Thoracic stretching
Postural reeducation
29
Q

Silhouette sign:

A

present when normal line of demarcation between two structures is partially or completely obliterated

30
Q

What is CT primarily used for?

A

Primarily for dx of tumors vs. calcifications or nodules

Can be ordered if normal CXR but abnormal PFTs

31
Q

Pulmonary Function Test (PFT)

A

Tests of lung volume and capacity

Total lung capacity (TLC) = vital capacity + residual volume

32
Q

Hyperventilation

A

PaCO2 <40 mm Hg

33
Q

Hypoventilation

A

PaCO2 >40 mm Hg

34
Q

Ventilatory failure

A

PaCO2 >50 mm Hg

35
Q

Alkolotic PaCO2:

A

less than 35 mmHg

36
Q

Acidic PaCO2:

A

greater than 45 mmHG

37
Q

Alkolotic HCO3

A

greater than 26

38
Q

Acidic HCO3:

A

less than 22

39
Q

Pneumothorax:

A

entry of air in pleural space

40
Q

Lung volumes with pneumothorax:

A

lung volume decreases
VQ mismatching increases
gas exchange impaired

41
Q

Lung volumes with hemothorax:

A

increase VQ mismatching
decrease lung compliance
atelectasis

42
Q

Normal FEV1

A

3.0 L

43
Q

Normal FVC:

A

4.0 L

44
Q

Normal FEV1/FVC:

A

75%

45
Q

Restrictive FEV1

A

2.5 L

46
Q

Restrictive FVC:

A

3.0 L

47
Q

Restrictive FEV1/FVC:

A

83%

48
Q

Obstructive FEV1

A

1.0 L

49
Q

Obstructive FVC:

A

4.0 L

50
Q

Obstructive FEV1/FVC:

A

25%

51
Q

Sympathomimetic:

A

stimulate adrenergic receptors

bronchodilation

52
Q

Adrenergic agnonists

A

stimulate adrenergic receptors

bronchodilation

53
Q

Sympatholytic:

A

inhibit adrengeric receptors

bronchoconstrict

54
Q

Adrenergic antagonists

A

inhibit adrengeric receptors

bronchoconstrict

55
Q

Parasympathomimetic

A

stimulate cholinergic receptors

bronchoconstrict

56
Q

Muscarinic agonists

A

stimulate cholinergic receptors

bronchoconstrict

57
Q

Parasymatholytics

A

inhibit cholinergic receptors

bronchodilation

58
Q

Muscarinic antagonists

A

inhibit cholinergic receptors

bronchodilation