Obstetric Hemorrhage, Cardio, Pulmo Flashcards

1
Q

Happens when there is premature separation of a normally implanted placenta

A

Abruptio placenta

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2
Q

Immediate event that can cause hemorrhage and subsequent abruptio placenta

A

Preeclampsia

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3
Q

This dangerous drug can cause vasoconstriction with resultant placental separation

A

Cocaine

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4
Q

Virchow’s triad in placental abruption

A

VIA Vaginal bleeding Increased uterine tone Abdominal pain

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5
Q

Diagnostic test for abruptio placenta where you put a blood sample in a test tube and positive if a clot forms within 6 minutes or forms and lyses within 30 minutes

A

Clot observation test

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6
Q

Most common obstetric cause of DIC

A

abruptio placenta

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7
Q

This intervention can be diagnostic and therapeutic in abruptio placenta

A

Amniotomy

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8
Q

What is the boundary threshold for a low lying placenta?

A

2cm

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9
Q

Most common pathophysiology of placenta previa

A

Defective decidual vascularization

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10
Q

Management of placenta accreta

A

Classical CS, hysterectomy

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11
Q

Septic abortion and chorioamnionitis are associated with what coagulation pathway?

A

Intrinsic pathway (endothelial damage)

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12
Q

Abruptio, amniotic fluid embolism, retained dead fetus and saline induced abortion is associated with what coagulation pathway?

A

Extrinsic

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13
Q

Syndrome characterized by widespread systemic activation of coagulation

A

DIC

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14
Q

The combination of nifedipine snd what other tocolytic agent can cause dangerous neuromuscular blockade?

A

Magnesium sulfate

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15
Q

Only well accepted risk factor of gestational hypertension

A

Primiparity

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16
Q

Classic presentation of placenta previa

A

Painless vaginal bleeding

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17
Q

Management of placenta previa is the placental edge is >2cm from os

A

Trial of labor

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18
Q

Management of placenta previa is the placental edge is <2cm from os

A

Vaginal delivery if possible

19
Q

Classification of placenta accreta if it invades the myometrium

20
Q

Classification of placenta accreta if it penetrates the myometrium and through the serosa

21
Q

2 most important risk factors in placenta accreta

A

Placenta previa Prior CS

22
Q

Hypertension without proteinuria occurring after 20 weeks AOG and BP returns to normal levels 12 weeks postpartum

A

Gestational hypertension

23
Q

BP 140/90 prior to pregnancy or before 20 weeks AOG and persists 12 weeks postpartum

A

Chronic hypertension

24
Q

What is the underlying etiology of proteinuria is seen with preeclampsia?

A

Increased capillary permeability

25
Renal change that occur in gestational hypertension
Glomerular endotheliosis
26
Mechanism in preeclampsia is placental implantation with replacement of ________ endothelium with trophoblasts
Spiral arteriole
27
Prevention of preeclampsia syndrome
High dose calcium Low dose aspirin
28
Management of severe preeclampsia if **\<34 weeks**
* Expectant management \<34 weeks * Admit to hospital at maternal ICU * Maternal-fetal evaluation for 24 hours * Magnesium sulfate for 24 hours * Antihypertensives for BP \>160/110 or MAP \>125 * Sonological monitoring: * Assess fetal size by US every 2 weeks * BPS + AFI at least twice weekly * Umbilical artery Doppler – once a week * NST - daily
29
Management of severe preeclampsia if \<23 weeks
Terminate pregnancy
30
Management of severe preeclampsia if 23-32 weeks
* Steroids (24-34 weeks AOG) * Betamethasone 12 mg/IM q24 hours for 2 doses * Dexamethasone 6 mg/IM q12 hours for 4 doses * Antihypertensives if needed * daily evaluation of maternal-fetal condition * Delivery if with indications * Delivery at 32-34 weeks
31
Known fetal side effect of hydralazine
Thrombocytopenia
32
Drug of choice for severe hypertension in pregnancy
Hydralazine
33
Drug of choice for gestational/chronic hypertension in pregnancy
Methyldopa
34
Side effect of labetalol
Fetal growth restriction
35
What is the target magnesium level in eclampsia prophylaxis?
4.8-8.4 mg/dl
36
Drug of choice for prevention of convulsions in severe preeclampsia
Magnesium sulfate
37
Preferred mode of delivery for cardiovascular disorders
Vaginal Epidural anesthesia
38
For patients with congenital heart disease, what is the most common adverse event encountered in pregnancy?
Arrhythmia
39
Most common etiology of CAP in pregnancy
Strep pneumoniae
40
Most frequent complication of pneumonia in pregnancy
PROM
41
Initial monotherapy for CAP
Macrolides
42
Fetal response to maternal hypoxemia
Decreased CO
43
Management of severe preeclampsia if **\>34 weeks**
stabilize mother and deliver * Mode of delivery * **\>34 weeks:** **vaginal delivery** if maternal, fetal and cervical conditions are **favorable** * **\<32 weeks**: consider **CS** due to reduced success in induction