Maternal Physio Flashcards

1
Q

Increase in cardiac output during pregnancy is attributed to

A

Decreased SVR

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2
Q

Cardiac output increases during

A

5 weeks AOG

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3
Q

Plasma volume expansion begins at

A

10-20 weeks

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4
Q

Heart is displaced ____ and _____ and rotated on its long axis

A

Left and upward

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5
Q

What causes the larger cardiac silhouette on CXR in pregnant women?

A

Apex moved laterally

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6
Q

Murmur heard in 90% of patients that is intensified during inspiration

A

Systolic murmur

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7
Q

Arterial pressure usually decreases to a nadir at how many weeks

A

24-26 weeks

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8
Q

Principal prostaglandin of endothelium that is increased during late pregnancy

A

Prostacyclin

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9
Q

Potent vasoconstrictor that stimulates secretion of ANP, aldosterone and catecholamines

A

Endothelin

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10
Q

Normal blood loss during vaginal delivery

A

500ml

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11
Q

Maternal blood expands during what trimester

A

2nd

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12
Q

Remission of autoimmune disorders is due to

A

Suppressed TH1 response

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13
Q

Hypervolemia averages 40-45% above nonpregnant blood volume during

A

32-34 weeks

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14
Q

Failure of TH1 suppresion may be related to the development of

A

Preeclampsia

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15
Q

Increased levels of these coagulation factors occur in pregnancy

A
4 F
Fibrinogen 
Factor 7
Factor 10
Flasminogen
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16
Q

WBC and platelet counts are____ during pregnancy

A

Increased WBC

Decreased platelets

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17
Q

Diaphragm rises about how many cms in pregnancy?

A

4cm

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18
Q

Subcostal angle widens how much during the 2nd half of pregnancy?

A

2cm

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19
Q

There is an increase of ___cm in thoracic circumference

20
Q

Physiologic dyspnea results from increase in _______ which lowers blood PCO2

A

Tidal volume

21
Q

This hormone lowers the threshold and increases sensitivity to CO2

A

Progesterone

22
Q

Softening of the isthmus is called

A

Hegar sign

23
Q

Uterine enlargement is most marked in the

24
Q

Main portion of the uterine wall with figure of 8 configuration

A

Middle layer

25
Softening and cyanosis of the cervix due to increased vascularity
Goodell sign
26
Produces progesterone during the first 6-7 weeks
Corpus luteum
27
Protein hormone secreted by the corpus luteum, decidua and placenta that remodels reproductive tract
Relaxin
28
Increased vascularity of the vagina that results to violet discoloration
Chadwick
29
Glands that become prominent in the breasts
Glands of montgomery
30
Postprandial hyperglycemia may be due to this hormone
Placental lactogen Estrogen Progesterone
31
Average weight gain during pregnancy
12.5kg
32
Carbohydrate metabolism in pregnant patients: what happens to blood sugar levels?
Mild fasting hypoglycemia Postprandial hyperglycemia Hyperinsulinemia
33
TAG, LDL, HDL and VLDL are all increased during what trimester
3rd
34
Leptin deficiency is associated with
Anovulation | Infertility
35
Abnormally elevated leptin results to
Preeclampsia | GDM
36
Right ureter is dilated more than the left because
Dextrorotated uterus
37
Bladder trigone is elevated during
12 weeks
38
Appendix is displaced in what direction during pregnancy
Upward and laterally
39
Focal, highly vascular swelling of the gums but regress spontaneously after delivery
Epulis of pregnancy
40
What happens to the liver size during pregnancy
Remains the same
41
This hormone impairs gallbladder contraction which results to increased stasis and cholesterol saturation
Progesterone
42
This hormone inhibits intraductal transport of bile acids
Estrogen
43
Principal source of GH secretion starting
17 weeks AOG
44
Major determinant of maternal insulin resistance after midpregnancy
Placental GH
45
This hormone prevents water transfer from fetus into maternal compartment to prevent fetal dehydration
Prolactin in amniotic fluid
46
TSH and HCG has identical
Alpha subunits
47
The only hormone in the adrenal gland that is decreased during pregnancy
DHEA | dhecreased