Maternal Physio Flashcards
Increase in cardiac output during pregnancy is attributed to
Decreased SVR
Cardiac output increases during
5 weeks AOG
Plasma volume expansion begins at
10-20 weeks
Heart is displaced ____ and _____ and rotated on its long axis
Left and upward
What causes the larger cardiac silhouette on CXR in pregnant women?
Apex moved laterally
Murmur heard in 90% of patients that is intensified during inspiration
Systolic murmur
Arterial pressure usually decreases to a nadir at how many weeks
24-26 weeks
Principal prostaglandin of endothelium that is increased during late pregnancy
Prostacyclin
Potent vasoconstrictor that stimulates secretion of ANP, aldosterone and catecholamines
Endothelin
Normal blood loss during vaginal delivery
500ml
Maternal blood expands during what trimester
2nd
Remission of autoimmune disorders is due to
Suppressed TH1 response
Hypervolemia averages 40-45% above nonpregnant blood volume during
32-34 weeks
Failure of TH1 suppresion may be related to the development of
Preeclampsia
Increased levels of these coagulation factors occur in pregnancy
4 F Fibrinogen Factor 7 Factor 10 Flasminogen
WBC and platelet counts are____ during pregnancy
Increased WBC
Decreased platelets
Diaphragm rises about how many cms in pregnancy?
4cm
Subcostal angle widens how much during the 2nd half of pregnancy?
2cm
There is an increase of ___cm in thoracic circumference
6cm
Physiologic dyspnea results from increase in _______ which lowers blood PCO2
Tidal volume
This hormone lowers the threshold and increases sensitivity to CO2
Progesterone
Softening of the isthmus is called
Hegar sign
Uterine enlargement is most marked in the
Fundus
Main portion of the uterine wall with figure of 8 configuration
Middle layer