Infectious Disease Flashcards
Drug of choice for bacterial vaginosis
Metronidazole
Treatment of syphilis in pregnancy
Benzathine Pen G IM single dose
Green yellow frothy discharge Strawberry cervix Metronidazole 2g single dose- until after 1st trimester; treat regardless if symptomatic Partners should be treated
Trichomonas
In trichomonas infection, breastfeeding must be withheld up to how many hours after the last dose?
12-24 hours
Most common manifestation of vulvovaginal candidiasis
Vulvar priritus
Recommended treatment for candiasis for pregnant women
- Azole creams: Butoconazole, clotrimazole, miconazole, terconazole (CDC STD Treatment Guidelines, 2010)
- Only topical azole therapies (cream, suppository, tablet), applied for 7 days, are recommended for pregnancy.
• Fluconazole is contraindicated.
Drug of choice for chlamydia in pregnancy
Treatment during pregnancy (CDC STD Guidelines, 2010)
- Azithromycin 1g PO as single dose, DRUG OF CHOICE or
- Amoxicillin 500mg PO TID for 7 days
Ophthalmia neonatorum Septic aborion PROM Chorioamnionitis May be seen in what infection
Gonorrhea
Treatment for gonorrhea
Uncomplicated GC infections in pregnancy (CDC STD Treatment Guidelines, 2010)
- Ceftriaxone, 250 mg IM, single dose or
- Cefixime, 400 mg/tab, single dose or
- Single dose injectible cephalosporin regimens PLUS:
- Azithromycin 1 gram PO single dose
- PLUS treatment for Chlamydial infection, unless it is excluded
Appears after penicillin treatment of syphilis characterized by uterine contractions accompanied by late fetal heart deceleration
Jarisch-Herxheimer reaction
Can women with HSV infection breastfeed?
Yes as long as there are no active lesions in the breast
Fetal cell-mediated and humoral immunity begin to develop during what age of gestation?
9-15 weeks AOG
What immunoglobulin is the primary fetal response to infection?
IgM
If given varicella and MMR vaccine, how long till you can get pregnant?
1 month after vaccination
Pregnant women without history should receive varicella zoster Ig if with significant exposure to a person infected within
96 hours of exposure
Varicella zoster Ig must be given to neonates if mother has clinical evidence when?
5 days before and up to 2 days after delivery
How many weeks AOG has a 90% chance of developing congenital rubella syndrome?
First 12 weeks
Most common single defect in congenital rubella
Sensorineural deafness
Heart defect in congenital rubella
PDA
Most common perinatal infection
CMV
Clostridium infection due to this species can cause septic abortion
C. perfringens
This bacterial infection can cause preterm labor, PROM and chorioamnionitis
Group B strep
Universal vaginal and rectal GBS screening culture is done at
35-37 weeks
Intrapartum Antimicrobial prophylaxis for GBS
Pen G