Fetal Growth Disorders, Abortion, Ectopic Flashcards

1
Q

Organ spared from effects of growth restriction

A

Brain

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2
Q

Fetal growth disorder when there is an early insult

A

Symmetric

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3
Q

Banana cerebellum is associated with what disease?

A

Arnold Chiari malformation

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4
Q

Strawberry cranium os associated with what disorder?

A

Edwards syndrome

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5
Q

Most common fetal cause of abortion

A

Blighted ovum

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6
Q

Common infectious cause of abortion in the 2nd trimester

A

Bacterial vaginosis

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7
Q

Nonviable genetically abnormal pregnancy due to an excess expression of paternal genes

A

Hydatidiform mole

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8
Q

What type of H mole occurs when there is generalized swelling of the placental villi with marked trophoblastic proliferation and absent fetal component

A

Complete H mole

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9
Q

This type of H mole occurs when there is 1 maternal and 2 paternal chromosomes and a milder form of trophoblastic invasion

A

Partial H mole

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10
Q

Most accurate non invasive imaging modality in detecting H mole

A

Ultrasound

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11
Q

Ultrasound in H mole will reveal this finding

A

Grape like or snowstorm like clusters

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12
Q

Chemoprophylaxis for H mole

A

Methotrexate

Actinomycin D

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13
Q

Post evacuation HCG monitoring for H mole:

A

1-2-1-2

1 week after suction curretage
Every 2 weeks until hcg becomes normal for 3 consecutive tests
Every 1 month for the first 6 months
Every 2 months for the next 6 months

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14
Q

When is pregnancy allowed after a normal HcG for a patient with previous H mole?

A

6 months

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15
Q

Vaginal bleedinfg, uterine enlargement, acute abdomen, rise in HCG levels for 2 determinations or persistently elevated levels for 6 months or more

A

Gestational Trophoblastic Neoplasia

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16
Q

GTN stage where it extends outside the uterus but confined to pelvic organs

A

Stage 2

17
Q

GTN stage where there is pulmonary metastasis

A

Stage 3

18
Q

Treatment for stage 1 GTN

A

Single agent- Methotrexate or actinomycin D

19
Q

Treatment for all other stages of GTN

A

EMACO with or winning hysterectomy

Etoposide
Methotrexate 
Actinomycin D
Cyclophosphamide
Vincristine
20
Q

Infectious cause of ectopic pregnancy

A

Chlamydia trachomatis

21
Q

Most catastrophic site of ectopic pregnancy

A

Decidua

Intersitial

22
Q

Gold standard for the diagnosis and treatment of tubal pregnancy

A

Laparoscopy

23
Q

Medical management for tubal pregnancy

A

Methotrexate

24
Q

Indications for methotrexate therapy in tubal pregnancy

A

Pregancy < 6 weeks
Tubal mass <3.5 cm
No cardiac activity
HCG <10-15k mIU/ml

25
Q

Is breastfeeding contraindicated when taking methotrexate?

A

Yes