Obesity and Lifestyle Choices Flashcards
1
Q
What is the major pathology associated with obesity?
A
diabetes
2
Q
What hormone is the major determinant of human weight?
A
leptin
3
Q
How much are fat cells capable of varying their size?
A
by 20 fold
4
Q
How long does it take for a fat cell to apoptose?
A
6 months of stable diet reduction
5
Q
What part of the brain regulates food intake?
A
the hypothalamus
6
Q
Which peptides stimulate appetite?
A
NPY and AgRP
7
Q
Which peptides suppress appetite?
A
POMC and CART
8
Q
What is adiponectin?
A
a hormone produced by fat cells which stimulates fatty acid oxidation, glucose uptake and lactate production
9
Q
What are the three features of metabolic syndrome?
A
hypertension, hyperlipidaemia and diabetes mellitus
10
Q
Which hormone stimulates appetite at meal times?
A
ghrelin
