nutrient - drug incompatibilities Flashcards

1
Q

A drug incompatibilities

A

hepatoxic drugs - A already hepatoxic

Warfarin (A toxicity leads to haemorrhage already)!

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2
Q

Which drugs can decrease thiamin levels

A
Antibiotics 
Diuretic
Contraceptive 
Alcohol 
Haemodialysis
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3
Q

What can impair riboflavin absorption/ decrease bioavailability

A

Caffeine
Alcohol
Chocolate
Antacids

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4
Q

which 2 drugs might pyridoxine reduce plasma levels of

A

phenobarbital (anticonvulsant)

phenytoin (antiepileptic)

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5
Q

what is the effect of barbiturates/anticonvulsants on D

A

increased catabolism = osteomalacia

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6
Q

what is effect of anti-tuberculosis drug isoniazid on D

A

inhibits hydroxylation in liver = osteomalacia

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7
Q

E - drug incomaptibilities

A

E thins blood - careful if on warfarin
may interfere with chemo (make it safer?)
may interfere with statins

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8
Q

E - drug incomaptibilities

A

E thins blood - careful if on warfarin
may interfere with chemo (make it safer?)
may interfere with statins

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9
Q

which drug should you not take K with

A

warfarin/other anti-coagulants - and avoid leafy greens! haemorrhage!

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10
Q

Which nutrient is most vulnerable to drug interactions

A

folate

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11
Q

which drugs if taken could increase the chance of folate deficiency

A

anti-cancer drugs
aspirin
antacids
oral contraceptives

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