Nucleic Acids - Structure and Function 4 Flashcards
hold nucleic acid duplex together, with two hydrogen bonds per A-T pair and three hydrogen bonds per G-C pair
hydrogen bonds
has a prominent major groove and a minor groove tracing the path of the helixx
B-form of DNA
proteins, such as ____________- bind in major and minor grooves and access the hydrogen bonds of the base pairs to read the sequences
transcription factors
A-form was identified by
Rosalind Franklin
relatively minor form of DNA that resembles the two strand of DNA
A-form
important in the duplex form of RNA and in RNA-DNA hybrids
A-form
Both A-form and B-form of DNA have the helix oriented at
right-handed form
True or False: Z-form has the same base pairing rules as A-form and B-form
True
How is the helices of Z-form DNA oriented?
left-handed helix
helix is rather stretched out
Z-forms
Why are there different topological forms of DNA?
due to superhelical tension and sequence bias
certain sequences tend to favor the flipping of B-form DNA into other forms
Sequence bias
favored by long stretches of alternating Gs and Cs
Z-DNA
short stretches of linear DNA duplexes exist in the __________ and have 10.5 base pairs per second
B-form
strands of DNA at the site of replication get unwound at the rate of
6000 rpm
