Nucleic Acid Flashcards

1
Q

They are Polymers of individual nucleotide monomer

A

NUCLEIC ACIDS

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2
Q

Nucleic acids are found in two basic
structural forms ___________

A

DNA
RNA

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3
Q

It is found in nucleus and mitochondria

A

DNA

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4
Q

It is the storage and transfer of genetic information

A

DNA

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5
Q

It is found in nucleus and cytoplasm

A

RNA

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6
Q

It is for the synthesis of protein

A

RNA

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7
Q

Meaning of RNA

A

ribonucleic acid

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8
Q

Meaning of DNA

A

deoxyribonucleic acid

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9
Q

They are the fundamental components of nucleotides

A

Phosphate group
Nitrogenous base
Pentose sugar

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10
Q

It Is named by changing the nitrogen base ending to

A

Nucleoside

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11
Q

Nitrogen base ending for purines

A

-osine

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12
Q

Nitrogen base ending for pyrimidines

A

-idine

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13
Q

Most common and abundant dna forms

A

B-DNA

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14
Q

It is the dehydrated B-DNA form

A

A-DNA

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15
Q

Left-Handed helical structure DNA form

A

Z-DNA

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16
Q

What are the steps in replication

A

Initiation - Unwinding of double helix
Priming
Elongation
Termination
Proofreading and correction

17
Q

What are the key enzymes in DNA replication

A

Helicase
Primase
DNA Polymerase
DNA Ligase

18
Q

Enzyme that Synthesizes an RNA primer

19
Q

Enzyme that Cleaves and unwinds short sections of DNA

20
Q

Enzyme that Catalyzes the formation of phosphate bridges between nucleotides

A

DNA Ligase

21
Q

Enzyme that serves 3 different functions

A

DNA Polymerase

22
Q

It relaxes the supercoiling of the double-stranded DNA while being unwind by helicase
or RNA polymerase

A

Topoisomerases

23
Q

Phosphate is derived from what?

A

Phosphoric acid (H3PO4)

24
Q

It is responsible for the ACIDIC nature of
nucleic acids

25
It is named using the name of the nucleoside followed by 5’-monophosphate.
NUCLEOTIDES
26
It is the nucleic acid backbone
SUGAR-PHOSPHATE
27
Founded the secondary structure of nucleic acids (model of DNA)
Watson and Crick
28
Chemical structure only allows bases to bind with specific other bases due to chemical structure.
COMPLEMENTARITY
29
In the chains, each end of the helix contains the 5' end of one strand and the 3' end of the other.
ANTIPARALLELISM
30
Structure that has sequence of the nucleotide
Primary structure
31
Structure with Helical Structure and Stabilized by H – bond
Secondary structure
32
Structure that deals with Supercoiling
Tertiary Structure
33
It is the process of denaturation
Melting
34
RNA to DNA interaction (reverse)
Transcription
35
RNA to Proteins interaction
Translation
36
DNA to DNA
Replication