Nucleic Acid Flashcards
They are Polymers of individual nucleotide monomer
NUCLEIC ACIDS
Nucleic acids are found in two basic
structural forms ___________
DNA
RNA
It is found in nucleus and mitochondria
DNA
It is the storage and transfer of genetic information
DNA
It is found in nucleus and cytoplasm
RNA
It is for the synthesis of protein
RNA
Meaning of RNA
ribonucleic acid
Meaning of DNA
deoxyribonucleic acid
They are the fundamental components of nucleotides
Phosphate group
Nitrogenous base
Pentose sugar
It Is named by changing the nitrogen base ending to
Nucleoside
Nitrogen base ending for purines
-osine
Nitrogen base ending for pyrimidines
-idine
Most common and abundant dna forms
B-DNA
It is the dehydrated B-DNA form
A-DNA
Left-Handed helical structure DNA form
Z-DNA
What are the steps in replication
Initiation - Unwinding of double helix
Priming
Elongation
Termination
Proofreading and correction
What are the key enzymes in DNA replication
Helicase
Primase
DNA Polymerase
DNA Ligase
Enzyme that Synthesizes an RNA primer
Primase
Enzyme that Cleaves and unwinds short sections of DNA
Helicase
Enzyme that Catalyzes the formation of phosphate bridges between nucleotides
DNA Ligase
Enzyme that serves 3 different functions
DNA Polymerase
It relaxes the supercoiling of the double-stranded DNA while being unwind by helicase
or RNA polymerase
Topoisomerases
Phosphate is derived from what?
Phosphoric acid (H3PO4)
It is responsible for the ACIDIC nature of
nucleic acids
PHOSPHATE