Enzymes

Question 1

a substance that slows down or stops the
normal catalytic function of an enzyme by binding to it.

Answer 1

Enzyme Inhibitor:

Question 2

Compete with the substrate for
the same active site

Answer 2

Competitive Inhibitors

Question 3

Binds to the enzyme at a location other than active site

Answer 3

Noncompetitive Inhibitors

Question 4

A noncompetitive enzyme inhibitor decreases enzyme activity by binding to a site on an enzyme other than the active site (T/F)

Answer 4

True

Question 5

An irreversible enzyme inhibitor inactivates enzymes by forming a strong covalent bond with the enzyme’s active site. (T/F)

Answer 5

True

Question 6

A process in which activation or inhibition of the first reaction in a reaction sequence is controlled by a product of the reaction sequence.

Answer 6

Feedback Control:

Question 7

An enzyme that catalyzes the transfer of a
functional group from one molecule to another

Answer 7

Transferase

Question 8

catalyze transfer of an amino group to a
substrate

Answer 8

Transaminases

Question 9

catalyze transfer of a phosphate group from
adenosine triphosphate (ATP) to a substrate

Answer 9

Kinases

Question 10

an enzyme that catalyzes a hydrolysis
reaction

Answer 10

Hydrolase

Question 11

an enzyme that catalyzes the addition of a group to a double bond or the removal of a group to form a double bond in a manner that does not involve hydrolysis or oxidation

Answer 11

Lyase

Question 12

It effects the removal of the components of
water from a double bond

Answer 12

Dehydratase

Question 13

It effects the addition of the components of
water to a double bonds

Answer 13

Hydratase:

Question 14

an enzyme that catalyzes the
isomerization (rearrangement of atoms) reactions.

Answer 14

Isomerase

Question 15

enzyme that catalyzes the formation of a
bond between two molecules involving ATP hydrolysis:

Answer 15

enzyme that catalyzes the formation of a
bond between two molecules involving ATP hydrolysis:

Question 16

Most enzymes have optimal activity in the pH range of 7.0 - 7.5 (T/F)

Answer 16

True

Question 17

Pepsin optimum pH

Answer 17

2.0

Question 18

Trypsin optimum pH

Answer 18

8.0

Question 19

Number of substrate molecules converted to
product per second per enzyme molecule under conditions of optimum temperature and pH

Answer 19

Turnover Number

Question 20

Enzyme has a pre-determined shape for the active site

Answer 20

Lock-and-Key model

Question 21

Lock-and-Key model has only substrate of specific shape can bind with active site (T/F)

Answer 21

True

Question 22

Substrate contact with enzyme will change the shape of the active site

Answer 22

Induced Fit Model

Question 23

Specificity: with an enzyme will catalyze a particular reaction for only one substrate

Answer 23

Absolute Specificity

Question 24

Absolute Specificity is most restrictive of all specificities (T/F)

Answer 24

True

Question 25

Specificity with enzyme can distinguish between stereoisomers.

Answer 25

Stereochemical Specificity

Question 26

Small organic molecules or Inorganic ions that are important for the chemically reactive
enzymes

Answer 26

Cofactors

Question 27

Enzyme that is composed only of protein (amino acid chains)

Answer 27

Simple enzyme

Question 28

Enzyme that has a nonprotein part in addition to a protein part.

Answer 28

Conjugated enzyme

Question 29

They are catalysts and are not consumed in the reactions

Answer 29

Enzymes

Question 30

The human body has 1000s of enzymes (T/F)

Answer 30

True

Question 31

Enzyme activity is dramatically affected by (3)

Answer 31

Alterations in pH
Temperature
Other protein denaturants

Question 32

Most enzymes are globular proteins (T/F)

Answer 32

True