NSAIDs Flashcards
1
Q
When are NSAIDs used? (excluding aspirin)
A
- mild/moderate/PRN pain management
- inflammatory mediated pain (RA, OA, gout)
2
Q
What are the ADRs of NSAIDs?
A
- gastric irritation, ulcers, bleeding
- bronchospasm
- renal impairment
- fluid retention
- CV risk (stroke/MI)
3
Q
NSAIDs contraindications
A
- Renal/hepatic failure
- HF
- Asthma
- Indigestion (ulcers)
- Dyscrasias (coagulation defects)
pregnancy, breastfeeding
4
Q
Interactions of NSAIDs (think of the effects it has)
A
- other NSAIDs e.g. aspirin = ++ GI bleed
- antiplts/anticoags
- ACEis/other nephrotoxic drugs
- low dose steroids e.g. prednisolone
- SSRIs
5
Q
Administration instructions for NSAIDs
A
take with/after food to minimise gastric irritation
6
Q
When to provide gastroprotection with NSAIDs and what drug?
A
> 65y
Previous peptic ulcer
Other GI disturbing drug e.g. corticosteroid
CVD/DM
PPI = lansoprazole/omeprazole
