NSAIDs Flashcards
1
Q
Ketorolac: Class
A
NSAID
-nonselective COX 1 and 2 inhibitor
2
Q
Ketorolac: Use
A
Pain relief
Antiinflammatory
3
Q
Ketorolac: Mechanism of Action
A
Inhibition of prostaglandin synthesis by competitive blocking of the enzyme cyclooxygenase (COX 1 & 2)
4
Q
Ketorolac: Dose
A
15 mg IV
5
Q
Ketorolac: Pharmacokinetics
A
Absorption: PO, IV, IM
Onset: 30 minutes
Duration of Action: 4 hours
Metabolism: Hepatic
Excretion: Renal
6
Q
Ketorolac: Contraindications
A
Decreased bone healing in Ortho cases
Bleeding Risk with inter cranial surgery
7
Q
Ketorolac: Considerations
A
Can cause bronchoconstriction with asthma
Dose decreased in elderly and CKD
Give during emergence