Nonopioid Analgesics (4)

Question 1

Acetaminophen

Answer 1

Brand Name: Tylenol

Classification: Nonnarcotic analgesic, antipyretic

Action: unknown but approximated to be inhibiting cyclooxygenase

Indications: mild-moderate pain, fever

Contraindications: hypersensitivity, alcoholism, chronic liver disease

Dose: 325-650mg

Routes: PO, IV

Adverse Effects: Rare

Other: can be liver toxic, use minimal dosage necessary

Question 2

Ibuprofen

Answer 2

Brand Name: Motrin, Advil

Classification: NSAID

Action: Anti-inflammatory, antipyretic through inhibition of prostaglandins

Indications: mild-moderate pain, fever, inflammation

Contraindications: hypersensitivity, bronchospasms, angioedema

Dose: 200-800mg

Routes: PO

Adverse Effects: nausea, vomiting, GI bleed, allergic reactions

Other: commonly causes gastric distress

Question 3

Ketorolac

Answer 3

Brand Name: Toradol

Classification: NSAID

Action: Anti-inflammatory and antipyretic through inhibition of prostaglandins

Indications: Mild-moderate pain, fever, inflammation, renal colic

Contraindications: hypersensitivity, bronchospasm, angioedema

Dose: 30mg (IV and elderly 60mg IM)

Routes: IV, IM

Adverse Effects: Nausea, vomiting, GI bleeding, allergic reactions

Other: commonly causes gastric upset, avoid entericcoated aspirin in chest pain

Question 4

Aspirin

Answer 4

Brand Name: Aspirin

Classification: NSAID

Action: Anti-inflammatory and antipyretic through inhibition of thromboxane A2

Indications: Mild-Moderate pain, Fever, Platelet Aggregation inhibitor

Contraindications: Hypersensitivity, Bronchospasm, Angioedema, Patient receiving monoamine oxidase inhibitor (MAOIs)

Dose: 350-650 mg

Routes: PO

Adverse Effects: Nausea, Vomiting, GI bleeding, Allergic reactions

Other: Commonly causes gastric upset. Avoid enteric-coated aspirin in chest pain