Neuromuscular Blocking Drugs (3)

Question 1

Succinylcholine

Answer 1

Brand Name: Anectine

Classification: Depolarizing neuromuscular blocker

Action: Binds to ACh receptors at the neuromuscular junction, causing depolarization and subsequent paralysis.

Indications: Rapid Sequence Intubation (RSI)

Contraindications: Hyperkalemia, Neuromuscular disease, Crush Injuries, Burns, Increased ICP, Severe Trauma

Dose: 1-2 mg/kg

Routes: IV, IO

Adverse Effects: Hyperkalemia, Bradycardia, Prolonged Paralysis, Malignant hyperthermia, Increased ICP, Muscle fasciculations, Trismus

Other: Should only be used by a skilled provider

Question 2

Vecuronium

Answer 2

Brand Name: Norcuron

Classification: Nondepolarizing neuromuscular junction, causing paralysis

Action: Binds to ACh receptors at the neuromuscular junction, causing paralysis

Indications: Rapid Sequence Intubation (RSI)

Contraindications: Hypersensitivity

Dose: 0.1-0.15 mg/kg

Routes: IV, IO

Adverse Effects: Skeletal Muscle Weakness, Malignant Hyperthermia, Apnea

Other: Should only be used by a skilled provider

Question 3

Rocuronium

Answer 3

Brand Name: Zemuron

Classification: Nondepolarizing neuromuscular blocker

Action: Binds to ACh receptors at the neuromuscular junction, causing paralysis

Indications: Rapid Sequence Intubation (RSI)

Contraindications: Hypersensitivity

Dose: 1 mg/kg

Routes: IV, IO

Adverse Effects: Hypertension, Hypotension, Skeletal muscle weakness, Malignant Hyperthermia, Apnea

Other: Should only be used by a skilled provider