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Pharm Unit 3 Drugs > Non-Medical Drugs > Flashcards

Non-Medical Drugs Flashcards

1
Q

Nalmefene (Revex) SE

A

May produce a prolonged withdrawal state (nausea, vomiting, piloerection, yawning)

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2
Q

Nalmefene (Revex) Class

A

Opiod antagonist

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3
Q

N-acetylcysteine (Mucomyst) class

A

Antioxidant

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4
Q

Cocaine class

A

CNS stimulant

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5
Q

LSD class

A

Schedule I Hallucinogen

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6
Q

Mescalineclass

A

Schedule I Hallucinogen

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7
Q

Psilocybin class

A

Schedule I Hallucinogen

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8
Q

Phencyclidine (PCP) class

A

Dissociative anesthetic

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9
Q

Marijuana (THC) class

A

Cannabinoid

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10
Q

Anandamide class

A

Endogenous cannabinoid

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11
Q

Dronabinol (Marinol) class

A

Synthetic THC

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12
Q

Nabilone (Cesamet) class

A

Synthetic THC

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13
Q

N-acetylcysteine (Mucomyst) MOA

A

Supplies sulfhydryl groups to glutathione; improves microcirculation, provides anti-inflammatory effect

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14
Q

Fomepizole (Antizol) MOA

A

Blocks alcohol dehydrogenase

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15
Q

Cocaine MOA

A

Blocks reuptake of dopamine, norepinephrine, and serotonin

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16
Q

LSD MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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17
Q

Mescaline MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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18
Q

Psilocybin MOA

A

Agonist at 5HT2A receptors on Raphe cell body –> inhibition of Raphe Nuclei firing –> increased sensory input; partial dopamine agonist

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19
Q

Phencyclidine (PCP) MOA

A

Antagonist of ion channel associated with NDMA receptor; agonist at mu opioid receptors

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20
Q

Amphetamines (Benzadrine) MOA

A

Indirect sympathomimetic (release biologic amines from nerve terminals in periphery and in CNS); dopamine most important

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21
Q

Marijuana (THC) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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22
Q

Anandamide MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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23
Q

Dronabinol (Marinol) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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24
Q

Nabilone (Cesamet) MOA

A

Hits cannabinoid receptors (CB1, CB2: G-protein coupled receptors)

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25
Q

Nalmefene (Revex) Therapeutics

A
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26
Q

N-acetylcysteine (Mucomyst) Therapeutics

A

Acetaminophen overdose

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27
Q

Fomepizole (Antizol) Therapeutics

A

Methanol & ethylene glycol poisoning

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28
Q

Cocaine Therapeutics

A

Topical anesthetic, combined vasoconstrictor and local anesthetic

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29
Q

LSD Therapeutics

A

Schedule I hallucinogen; model hallucinogen against which all others compared; limited studies in psychoanalysis, alcoholism, autistic children, and terminal cancer patients

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30
Q

Mescaline Therapeutics

A
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31
Q

Psilocybin Therapeutics

A
32
Q

Phencyclidine (PCP) Therapeutics

A
33
Q

Amphetamines (Benzadrine) Therapeutics

A

Narcolepsy, ADHD

34
Q

Marijuana (THC) Therapeutics

A

Schedule I hallucinogen; anti-emetic, anti-nausea, and appetite stimulate for cancer chemotherapy and AIDS patients; analgesic for neuropathic pain; potentially: glaucoma, asthma, anxiolytic, migraine, and multiple sclerosis treatment

35
Q

Anandamide Therapeutics

A

Endogenous cannabinoid

36
Q

Dronabinol (Marinol) Therapeutics

A

Schedule III drug; anti-emetic, anti-nausea, and appetite stimulate for cancer chemotherapy and AIDS patients

37
Q

Nabilone (Cesamet) Therapeutics

A

Schedule II drug; treatment-resistant nausea and vomiting, weight loss and anorexia in AIDS patients

38
Q

Nalmefene (Revex) Important SE

A
39
Q

N-acetylcysteine (Mucomyst) Important SE

A
40
Q

Fomepizole (Antizol) Important SE

A
41
Q

Cocaine Important SE

A
42
Q

LSD Important SE

A
43
Q

Mescaline Important SE

A
44
Q

Psilocybin Important SE

A
45
Q

Phencyclidine (PCP) Other SE

A

Dissociation, confusion, ataxia, marked nystagmus

46
Q

Amphetamines (Benzadrine) Other SE

A

Tremor, anxiety, irritability, confusion, possibly paranoid state

47
Q

Marijuana (THC) Other SE

A

May impair reproductive function in adolescents; heavy use may impair development of very young users; possible respiratory damage due to tar

48
Q

Anandamide Important SE

A
49
Q

Dronabinol (Marinol) Important SE

A
50
Q

Nabilone (Cesamet) Important SE

A
51
Q

Nalmefene (Revex) Important SE

A
52
Q

N-acetylcysteine (Mucomyst) Important SE

A
53
Q

Fomepizole (Antizol) Important SE

A
54
Q

Cocaine Important SE

A
55
Q

LSD Important SE

A
56
Q

Mescaline Important SE

A
57
Q

Psilocybin Important SE

A
58
Q

Phencyclidine (PCP) Other SE

A

Dissociation, confusion, ataxia, marked nystagmus

59
Q

Amphetamines (Benzadrine) Other SE

A

Tremor, anxiety, irritability, confusion, possibly paranoid state

60
Q

Marijuana (THC) Other SE

A

May impair reproductive function in adolescents; heavy use may impair development of very young users; possible respiratory damage due to tar

61
Q

Anandamide Important SE

A
62
Q

Dronabinol (Marinol) Important SE

A
63
Q

Nabilone (Cesamet) Important SE

A
64
Q

Nalmefene (Revex) Misc

A
65
Q

N-acetylcysteine (Mucomyst) Misc

A
66
Q

Fomepizole (Antizol) Misc

A

Very expensive

67
Q

Cocaine Misc

A

Rapidly hydrolyzed by plasma cholinesterase; crack is the free base form

68
Q

LSD Misc

A

Oxidized in liver; cross tolerance with mescaline and psilocybin

69
Q

Mescaline Misc

A

Cross tolerance with LSD and psilocybin

70
Q

Psilocybin Misc

A

Cross tolerance with mescaline and LSD

71
Q

Phencyclidine (PCP) Misc

A

Long half-life due to being highly lipid soluble and having active metabolites

72
Q

Amphetamines (Benzadrine) Misc

A

Others: dextroamphetamine (Dexedrine), methamphetamine (Desoxyn), methylphenidate (Ritalin)

73
Q

Marijuana (THC) Misc

A

Active ingredient is delta-9-tetrahydrocannabinol; metabolized by P450, with chronic use inducing enzyme; highly lipid soluble

74
Q

Anandamide Misc

A
75
Q

Dronabinol (Marinol) Misc

A
76
Q

Nabilone (Cesamet) Misc

A

Less psychoactive side effects than marijuana

Pharm Unit 3 Drugs (13 decks)

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