Non Hodgkin Lymphoma Flashcards

1
Q

how do we classify lymphoid malignancies

A

as B cell derived (are 70% of all NHL) or T cell derived (associated with angineural lymphoma)

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2
Q

clinical features of NH lymphomas

A

B symptoms, nausea, compression syndromes, SVC syndrome, dyspnea, orthopnea, refractory pruritus

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3
Q

diagnostic pathway of NHL

A
  • excisional biopsy or FNA for lymph nodes

- immunophenotype

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4
Q

main therapeutic options of NHL

A
  • radiation
  • bone marrow biopsy
  • chemo (RCHOP), monoclonal antibodies, radiotherapy
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5
Q

which is more common HL or NHL

A

NHL is 5x more common than HL

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6
Q

an elevated LDH means

A

poor prognosis

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7
Q

chromosome in mantle cell lymphoma

A

ch 11 gene or cyclin D1 protein and ch 14 for immunoglobulin heavy chain

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