Nitromidazoles Flashcards
1
Q
Name the two types of nitromidazoles
A
Metronidazole and tinidazole
2
Q
Key indications for metronidazole
A
c diff, cellulitus, diabetic foot infection, H. pylori, tetanus
3
Q
Common SE of metronidazole
A
Dry mouth, myalgia, nausea, metallic taste, GI disturbance, oral mucositis, furred tongue
4
Q
Metronidazole activity against
A
anaerobic bacteria and protozoa
5
Q
Pt counselling
A
W or after food
AVOID ALCOHOL - causes dilsulfriam-like reaction
6
Q
Which out of the two nitromidazoles has a longer duration of action
A
Tinidazole
7
Q
Mechanism of action of nitromidazoles
A
Narrow-spectrum ,bactericidal - inhibits DNA synthesis
