nitriles reaction Flashcards
1
Q
nitrile and acidic hydrolysis
A
CH3CN+2H2O+HCl=CH3COOH+NH4Cl
2
Q
nitrile and alkali hydrolysis
A
CH3CN+H20+NaOH=CH3COONa+NH3
3
Q
Haloalkane plus cn- with ethanol
A
CH3CH2Br+CN-=CH3CH2CN+Br
4
Q
aldehyde/ketone plus H+/NaCN
A
CH3COH+CN-=CH3COH2CN
5
Q
Haloalkane plus ethanolic ammonia
A
CH3CH2Br+NH3=CH3CH2NH2+Br-
6
Q
acyl chloride plus ammonia
A
amide
7
Q
nitrile to amine
A
add H2 and nickel catalyst
8
Q
reduction of nitrile
A
CH3CN+ 4[H]=CH3CH2NH2
9
Q
longer chain amino acids are better bases because?
A
stronger base because electrons move toward the N
the lone pair on the N delocalizes around the ring
so electron pair more easily donated
