NEW!! Psych Meds - ANTIDEPRESSANTS - with both names, cuz dammit we need to pass!! Flashcards
What is the mechanism of action for antidepressants?
They decrease the reuptake of serotonin (5HT) and sometimes norepinephrine.
Antidepresants may cause ______ effects
anticholinergic (against cholinergic = fight or flight)
Tricyclics work by ….
blocking reuptake of 5HT and NE
What is the danger of giving tricyclics?
can be used to commit suicide.
Tricyclics require an _____ before administering. Side effects include _________, orthostatic hypotension, confusionm arrhythmias, and weight gain. Do not have this with alcohol
ecg
photophobia
Generics for tricyclics end in triptyline and pramine.
Amitriptyline Nortriptyline Protriptyline Trimipramine Amoxapine Imipramine Desipramine Clomipramine Doxepin
Tofranil can be used to treat depression and bedwetting. What is the generic name?
imipramine - immapraying TO feel less fragile
Tofranil - To be fragile sucks, take this TO Feel less fragile.
No trick for this
The following are trade names for tricyclic antidepressants….
Elavil - elevates your mood
Asendenin - ascendin attitudes
Tofranil - To be fragile sucks, take this TO Feel less fragile.
Anafranil - am not fragile anymore
Norpramin - no more prayin, you gonna feel better after this
Aventyl - vent to feel better
Sinequan -
Vivactil - feeling vivacious
Surmontil - surmont your depression
This type of antidepressant inhibits the enzyme that breaks down dopamine and tyramine….
MAOI
If a person eats food too high in tyramine while taking an MOAi, what is worst case scenario?
Hypertensive crisis - eating too much tyramine can lead to intracranial bleeding.
HSNH
Headache, stiff neck, N/V, hypertension
What is the one MAOi that you can use without watching Tyramine in your diet?
selegiline (Emsam)
selebrating eating
gim ‘emsam of them tyramines.
MOAI generic names are all over the place….
Isocarboxazid
Tranylcypromine
Moclobemide
Phenelzine
Isotranylmoclophenel
MAOI trade names include
Marplan
Nardil
Parnate
Manerix
MarNarParMan
SSRIs work by….
Inhibiting serotonin reuptake
what can we use SSRIs to treat?
Depression
OCD
GAD
PTSD