NEUTROPENIA Flashcards

1
Q

what is neutropenia

A

low neutrophil count (<1.5x10^9/L)

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2
Q

what does neutropenia increase risk of

A
  • infections
  • sepsis
  • especially in chemotherapy
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3
Q

tx of neutropenia

A

Recombinant human granulocyte-colony stimulating factor (rhG-CSF)
- filagrastim
- lenograstim
- lipefilgrastim

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4
Q

How does rhG-CSF work

A
  • stimulates neutrophil production
  • redcues duration of chemo induced neutropenia - dec incidence of febrile neutropenia
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