SICKLE-CELL ANAEMIA Flashcards

1
Q

What is sickle cell anaemia

A

deformed and less flexible RBC

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2
Q

what is sickle-cell crisis

A
  • acute complication
  • restricted blood supply to organs
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3
Q

sickle-cell crisis tx

A

immediate hospitalisation
- fluid replacement
- analgesia
- treat any infections

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4
Q

complications caused by sickle-cell crisis

A
  • anaemia
  • leg ulcers
  • renal failure
  • susceptibility to infections
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5
Q

tx if pt develops haemolytic anaemia

breakdown of RBC

A
  • increase folate
  • folic acid
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6
Q

When is hydroxycarbamide given

A

to reduce frequency of painful crises and reduce transfusion requirements

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