Neurulation and neural crest Flashcards
1
Q
neurulation
A
• Neuroectoderm – Neural plate – Neural groove – Neural folds – Neural tube
-neural crest cells
2
Q
when does neural tube close?
A
end of week 3
3
Q
when does rostral neuropore close?
A
day 25
4
Q
when does caudal neuropore close?
A
day 28
5
Q
primary neurulation
A
brain and lumbar region closure
6
Q
secondary neurulation
A
sacral and coccyx region (occurs after primary)
7
Q
neural crest derivatives
A
- neurons (spinal ganglia, autonomic ganglia)
- schwann cells, satellite cells
- pia and arachnoid matter
- pigments cells
- endocrine cells
- bone and cartilage of face
- parts of heart
- teeth
8
Q
spinal bifida occulta
A
- failure of caudal neuropore to close at appropriate time
- unfused vertebral arch
9
Q
miningocele
A
- cyst like protusion out of back has mininges and cysts filled with CSF
- no formation of neural or vertebral arches
10
Q
mingomyelocele
A
- cyst covered with meninges
- spinal cord located in cyst
11
Q
myelocele (myeloschisis)
A
- spinal cord is open
- neural tube doesnt close
12
Q
what neural tube defects can be found by increased levels of alpha-fetal protein in ammnitoic fluid?
A
- meningocele
- meningomyelocele
- myelocele
13
Q
what disease are from failure of rostral neuropore to close at appropriate time?
A
- anencephaly
- encephalocele (with or without brain tissue)
14
Q
Meninx Primitiva
A
– Mesoderm in origin – Derived from cells of the sclerotome – Neural crest cells migrate and mingle
15
Q
Pachymeninx
A
– (dura mater - mesoderm)
