Neurotransmitters Flashcards

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1
Q

ACh receptors

A

Ionotrophic: nicotinic
Metabotrophic: muscarinic

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2
Q

ACh function

A
Learning
Memory
Attention
Neuromuscular function
Alzheimer's
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3
Q

ACh group

A

Biogenic amine

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4
Q

Serotonin production site

A

Raphe nuclei in medulla and pons

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5
Q

Serotonin receptors

A

At least 7 different receptors

Most inhibitory and metabotrophic

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6
Q

Serotonin function

A

Regulation of mood, control of eating, onset of sleep, control of pain
Ecstasy, shrooms, LSD, SSRIs

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7
Q

Serotonin group

A

Monoamines

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8
Q

Dopamine production site

A

VTA, substantia nigra

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9
Q

DA receptors

A

Metabotrophic

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10
Q

DA function

A

Reward mechanisms
Attention
Schizophrenia (too much)
Parkinson’s (too little)

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11
Q

DA group

A

Catecholamines

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12
Q

Norepinephrine (NA) production sites

A

Locus coeruleus

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13
Q

NA receptor

A

Inhibitory in CNS (alert, wakefulness)
Excitatory in PNS (target organs of sympathetic NS)
Epinephrine: metabotrophic

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14
Q

NA functions

A

General arousal
Orienting
Depression
Cocaine, amphetamines

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15
Q

NA group

A

Catecholamines

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16
Q

GABA receptors

A

Ionotrophic

17
Q

GABA function

A

Local, almost always inhibitory

18
Q

GABA group

A

Amino acid

19
Q

Glutamate receptor

A

Ionotrophic (3)

1 metabotrophic

20
Q

Glutamate function

A

Learning and memory

Almost always excitatory

21
Q

Glutamate group

A

Amino acid

22
Q

Anandamide receptor

A

Cannabinoid receptors: interfere with 5-HT receptor

23
Q

Anandamide functions

A

THC, chocolate

Mood, thinking, sensory perception, coordination, memory

24
Q

Anandamide group

A

Neuromodulator

25
Q

Neurotransmitter

A

Brain chemicals that communicate info throughout brain and body
Relay signals between neurons

26
Q

Ionotrophic receptor

A

Transmitter binding to receptors causes ion channel to open

Fast and short term

27
Q

Metabotrophic receptor

A

G-protein mediated
Slow, long-lasting
Uses energy, requires metabolism

28
Q

Identification of neurotransmitter:

A
  1. Chemical and enzyme exist in presynaptic terminal
  2. Chemical released by action potential
  3. Chemical applied to synapse artificially induces PSPs
  4. Blocking release presynaptically induces postsynaptic changes
29
Q

Agonist

A

Drug works with neurotransmitter

30
Q

Antagonist

A

Drug works against neurotransmitter

31
Q

Acetylcholine: production site

A

Nucleus Basalis of Meynert

Septal Nuclei