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Neuro > Neurotransmitters > Flashcards

Neurotransmitters Flashcards

1
Q

cocaine

A

blocks dopamine reuptake, leading to enhanced dopamine (pleasure) signals

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2
Q

amphetamines

A

enter presynaptic neuron, enter dopamine-filled vesicles, allows release of dopamine through pores

increased HR, BP

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3
Q

ecstasy

A

increases serotonin

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4
Q

morphine

A

binds to receptors for endorphins

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5
Q

drug abuse involves

A

reward via mesolimbic pathway

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6
Q

drug addiction involves

A

activation beyond the mesolimbic pathway

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7
Q

reward pathway

A

dopamine from VTA to NAc

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8
Q

nucleus accumbens

A

pleasure area (NAc)

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9
Q

Ach: Primary postsynaptic effect

A

excitatory

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10
Q

Glutamate: : Primary postsynaptic effect

A

excitatory

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11
Q

GABA: : Primary postsynaptic effect

A

inhibitory

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12
Q

Glycine: Primary postsynaptic effect

A

inhibitory

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13
Q

Catecholamines: Primary postsynaptic effect

A

modulatory

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14
Q

Serotonin (5-HT): Primary postsynaptic effect

A

modulatory

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15
Q

Histamine:: Primary postsynaptic effect

A

modulatory

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16
Q

endocannabinoids: Primary postsynaptic effect

A

inhibits release of lipids

17
Q

Ach: Precursor

A

choline + acetyl CoA

18
Q

Glutamate: Precursor

A

glutamine

19
Q

GABA: Precursor

A

glutamate

20
Q

Glycine: Precursor

A

serine

21
Q

Catecholamines: Precursor

A

tyrosine

22
Q

Serotonin: Precursor

A

tryptophan

23
Q

Histamine: Precursor

A

histidine

24
Q

Ach: Removal mechanism

A

AChEase

25
Q

Glutamate, GABA, Glycine: Removal mechanism

A

transporters

26
Q

Neuropeptides: Removal mechanism

A

proteases

27
Q

ACh: Major RLS enzyme

A

CAT

28
Q

Glutamate: Major RLS enzyme

A

glutaminase

29
Q

Glycine: Major RLS enzyme

A

phosphoserine

30
Q

GABA: Major RLS enzyme

A

GAD

31
Q

Catecholamines: Major RLS enzyme

A

tyrosine hydroxylase

32
Q

Serotonin: Major RLS enzyme

A

tryptophan hydroxylase

33
Q

Histamine: Major RLS enzyme

A

histidine decarboxylase

Neuro (15 decks)

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