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Neuro > ANS Pharmacology > Flashcards

ANS Pharmacology Flashcards

1
Q

Direct-acting sympathomimetics: non-selective

A

Norepinephrine (α>β1> β2)

Epinephrine (β≥α; dose/route dependent)

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2
Q

Direct-acting sympathomimetics: beta 1=beta 2

A

Isoproterenol

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3
Q

Direct-acting sympathomimetics: Beta 1> beta 2

A

dobutamine

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4
Q

Direct-acting sympathomimetics: beta 2 agonists

A

Albuterol, Salmeterol, Terbutaline

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5
Q

Direct-acting sympathomimetics: beta 3 (nonselective) agonists

A

clenbuterol

used illicitly in US, and dopamine

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6
Q

Indirect-acting sympathomimetics

A

Amphetamine (and cathinone derivatives),
Cocaine,
Dopamine,
Ephedrine,
Tyramine (interacts with MAO Inhibitors primarily)

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7
Q

Alpha-adrenergic antagonists: Nonselective

A

Phentolamine (peripheral)

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8
Q

Alpha-adrenergic antagonists: alpha 1 antagonist

A

prazosin (peripheral)

1a selective: tamsulosin (prostate)

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9
Q

Alpha-adrenergic antagonists: alpha 2 antagonist

A

Yohimbine (central)

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10
Q

alpha1 agonist

A

phenylphrine (direct)

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11
Q

alpha2 agonist

A

clonidine (central)

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12
Q

Non-selective beta1 and beta2 antagonists

A

propanolol

timolol (ocular

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13
Q

selective beta 1 antagonists

A

metoprolol
atenolol
esmolol (short acting

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14
Q

beta and alpha antagonist

A

labetolol

carvedilol

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15
Q

Benzodiazepines (GABA agonists):

A

diazepam

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16
Q

diltiazem/verapamil

A

Calcium channel antagonists (blockers):

cardiac > peripheral

17
Q

Nifedipine/amlodipine

A

Calcium channel antagonists (blockers):

peripheral > cardiac

18
Q

Vasodilators

A

Nitroglycerin (venous > arterial)

19
Q

Acetylcholine, Pilocarpine, Muscarine

A

Muscarinic receptor agonists

20
Q

Nicotine

A

Nicotinic N receptor agonist

21
Q

Physostigmine

A

Carbamate (Spontaneously Reversible) Cholinesterase inhibitors

(centrally and peripherally active)

22
Q

Pyridostigmine

A

Carbamate (Spontaneously Reversible) Cholinesterase inhibitors

(peripherally restricted)

23
Q

Organophosphate Cholinesterase inhibitor (

A

Malathion (pesticide)

Sarin (warfare agent)

24
Q

Pralidoxime (2PAM)

A

Cholinesterase reactivator

25
Q

atropine

A

muscarinic antagonist

26
Q

scopolamine

A

muscarinic antagonist

27
Q

muscarinic antagonist- ocular

A

tropicamide

28
Q

muscarinic antagonist- inhaled

A

ipratropium

29
Q

Succinylcholine

A

(depolarizing neuromuscular blockade)

30
Q

Non-depolarizing (competitive) nicotinic M receptor antagonists:

A

d-Tubocurarine (curare)

Vecuronium, Rocuronium

31
Q

Botulinum toxin

A

Inhibit ACh release at NMJ primarily

Neuro (15 decks)

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