Neurotransmisores 2 Flashcards

1
Q

Síntesis de serotonina

A

Se sintetiza a partir del triptófano en los núcleos de Rafe del SNC.

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2
Q

Funciones de serotonina

A
  • Movimientos del intestino
  • Regula nauseas
  • Regula estado de ánimo
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3
Q

Tipos de receptores de serotonina

A

Metabotrópicos
Ionotrópicos

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4
Q

Receptores metabotropicos de serotonina

A

5-HT 1, 2, 4, 5, 6, 7

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5
Q

Receptores ionotrópico de serotonina

A

5HT3

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6
Q

Síntesis de histamina

A

A partir del aminoácido histidina en el hipotálamo.

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7
Q

Función de histamina

A

En SN controla la producción de otros neurotransmisores
En sistema inmune: promueve la inflamación y en exceso enfermedades como el asma.

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8
Q

Receptores de histamina

A

Metabotropicos h1- 4

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9
Q

Antagonsita de receptor H1 (Gq) de histamina

A

Loratadina. Reduce asma.

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10
Q

a que clasificación de aminoácidos pertenecen los aas neurotransmisores

A

AAS no esenciales

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11
Q

NT aminoácidos

A

-Glutamato
- Aspartato
- GABA
- Glicina

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12
Q

aminoácidos excitatorios

A

Glutamato y aspartato

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13
Q

Aminoácidos inhibitorios

A

GABA y glicina

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14
Q

Principal neurotransmisor excitatorio del SNC (75%)

A

Glutamato

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15
Q

Vias de síntesis de glutamato

A
  1. alpha cetogluatato (ciclo de krebs) mediante GABA- transaminasa
  2. Vía glutamina mediente glutaminasa
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16
Q

Función de glutamato

A

Principal mediador de la información sensorial, motora, cognitiva, emocional e interviene en la formación de la memoria.

17
Q

Receptores ionotropicos de glutamato

A

AMPA. Kainato y NMDA

18
Q

Receptores matabotropicos de gluatamato

A

mGluR 1- 7

19
Q

Activación de canales de NMDA:

A

Se tienen que unir a glicina
Esta bloqueado por Mg que se libera cuando la célula se despolariza.
Deja pasar cationes (Ca y Na)