Neurosurgery/Neurology Flashcards
ICP cushings triad
Widened pulse pressure
Bradycardia
Irregular breathing
Raised ICP treatment
IV mannitol
Controlled hyperventilation
Head elevation
Unilateral dilated pupil and no light response in raised ICP
CN III compression may secondary herniation
Unilateral dilated pupil and exagerated light response in raised ICP
Optic nerve injury
CT scan immedietely when
GCS <13 initially or <15 after 2 hours
2 or more episodes vomiting
Skull fracture
Neurological deficit
CT scan within 8h
Age >65
Clotting disorders
Dangerous mechanism
Linked to SAH
Intracranial aneurysm - APKD
Diagnose SAH
1) CT head
2) LP after 12 hours - xanthochromia
SAH treatment
Coil by interventional radiologist
Nimodepine - prevent vasospasm
Subdural haemorrhage identify
High impact trauma
Fluctuating consciousness
Acute v chronic bleed CT
Acute - hyperdense
Chronic - hypodense, often subdural
Vessels in subdural bleed
Bridging veins
Vessels in extradural bleed
Middle meningeal artery
Identify extradural bleed
Low impact trauma, often young
Loses, regains then loses consciousness again (lucid interval)
Diagnose hydrocephalus
CT head
Treatment hydrocephalus
Acute - external ventricle drain
Long term - ventriculoperitoneal shunt
Triad of normal pressure hydrocephalus
Elderly:
- urinary incontinence
- dementia
- gait abnormality
Most common metastasis to brain
Lung cancer
Brain tumour worst prognosis
Astrocytoma (glioblastoma multiforme
Types of focal seizure
Focal aware
Focal impaired
Always starts specific region brain
Types of generalised seizure
Tonic clonic (grand mal) Tonic Clonic Typical absence (petit mal) Atonic
Starts both sides brain, always unconscious
Diagnose epilepsy
After first seizure:
- EEG
- MRI
Treat seizure
1) Give 5 mins
2) Benzo rectal/under tongue
3) Hospital - status epilapticus
Treatment epilepsy
Start epileptic after second seizure, or after first if:
- neurological deficit
- abnormal brain imaging
- abnormal EEG
Treatment generalised tonic clonic seizure
Sodium valproate
Treatment absence seizure
Sodium valproate or ethosuximide
Treatment myoclonic seizure
Sodium valproate
Treatment focal seizure
Carbamazepine or lamotrigine
Temporal seizure
Automatism (lip smacking, grabbing)
Frontal seizure
Jacksonian march
Post-ictal weakness
Parietal seizure
Paraesthesia
Occipital seizure
Visual
Identify infantile spasm
First few weeks of life
Saalam attack (flexion of head and extension of arms)
Poor prognosis
Identify absense seizure in kids
Onset 4-8y
Lasts few seconds to 30 with quick recovery, many per day
Identify Lennox-Gastraut syndrome
Onset 1-5y
Infantile spasm in past
Atypical absence, fall, jerk
Identify benign rolandic epilepsy
Paraesthesia on waking up
Identify juvenile myoclonic epilepsy
Onset teens
Infrequent generalised seizures
Migraine treatment
1) Triptin and NSAID
2) Non-oral metochlopramide
Migraine prevention
1) Topiramate or propranolol
PD plus syndromes
Multiple system atrophy - autonomic dysfunction
Dementia with lewy body
Progressive supranuclear palsy - problem moving eyes
PD treatment
1) Levodopa
2) Dopamine agonist, MAO-B inhibitor or COMT inhibitor to adjunct
PD treatment most common cause impulse control problems
Dopamine agonist therapy
PD treatment biggest effect on motor function and ADL
Levodopa
PD treatment most adverse effects
COMT inhibitor
PD treatment most hallucination risk
Dopamine agonist
Example dopamine receptor agonist
Bromocriptine
Cabergoline
Example MAOB inhibitor
Selegiline
Example COMT inhibitor
Etacapine
Diagnose temporal arteritis
Temoral artery biopsy - multinucleated giant cells
Treatment temporal arteritis
Urgent high dose glucocorticoid:
- prednisolone if no visual lose
- IV methylprednisolone if visual loss