Diabetic Drugs Flashcards

1
Q

Mechanism DDP4 inhibitors

A

Decrease peripheral breakdown of incretins

oral

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2
Q

-gliptin

A

DDP4 inhibitors

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3
Q

DPP4 and weight

A

No weight gain

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4
Q

GLP-1 mechanism

A

Increase insulin secretion and inhibit glucagon

SC

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5
Q

Exenatide

A

GLP-1

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6
Q

Drug used instead of insulin later line if BMI>35

A

GLP-1

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7
Q

Thiazolidinediones adverse

A

Weight gain
Fluid retention - contra HF
Bladder cancer - contra

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8
Q

Mechanism thiazolidediones

A

Reduce peripheral insulin resistance

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9
Q

Pioglitazone

A

thiazolidediones

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10
Q

Sulfonylurea mechanism

A

Increase pancreatic insulin secretion

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11
Q

Sulphonylurea adverse

A

Hypoglycaemia

Weight gain

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12
Q

Gliclizide

A

Sulphonylurea

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13
Q

SGLT-2 inhibitor mechanism

A

Increase glucose excretion in urine

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14
Q

SGLT-2 adverse

A

Fourniers gangrene

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15
Q

Drugs to lose weight

A

SGLT2

GLP1

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16
Q

-glioflozin

A

SGLT-2 inhibitors