Diabetic Drugs Flashcards
Mechanism DDP4 inhibitors
Decrease peripheral breakdown of incretins
oral
-gliptin
DDP4 inhibitors
DPP4 and weight
No weight gain
GLP-1 mechanism
Increase insulin secretion and inhibit glucagon
SC
Exenatide
GLP-1
Drug used instead of insulin later line if BMI>35
GLP-1
Thiazolidinediones adverse
Weight gain
Fluid retention - contra HF
Bladder cancer - contra
Mechanism thiazolidediones
Reduce peripheral insulin resistance
Pioglitazone
thiazolidediones
Sulfonylurea mechanism
Increase pancreatic insulin secretion
Sulphonylurea adverse
Hypoglycaemia
Weight gain
Gliclizide
Sulphonylurea
SGLT-2 inhibitor mechanism
Increase glucose excretion in urine
SGLT-2 adverse
Fourniers gangrene
Drugs to lose weight
SGLT2
GLP1